Bloodlines in generations

[QUOTE=vineyridge;5972451]
If you’re talking about me, I’ve recently learned that Relaunch is about average for TBs in racing where soundness is concerned. He did have a tendency to throw back at the knee, though.

And Vice Regent is becoming a good lines for event horses, if results are any indication. A couple of generations back is a very good place for him. This is also from new results research.

It’s really quite a nice TB pedigree for sport.

Edited to add: Years ago I saw a chart detailing the color possibilities for a colored corn hybrid, and the FI was fairly simple. But by the time you got to F3 the diversity was amazing. This was from breeding Hybrids to hybrids.[/QUOTE]

Viney, in case YOU were talking about ME now … scratching my head a little (gosh, this is getting more confusing than genetics) then no, I wasn’t talking about you. LOL!~ Honest.

What’s the “problem” with Northern Dancer, anyway, though?

Thanks Kathy :winkgrin: I should have been more descriptive in word choice :lol: but I couldn’t think of a way to illustrate what I was trying to get across.

I tell you guys, when I sit back and reflect on breeding and appreciate the significance of all this, then IMO breeding is more of a crapshoot than one wants to admit. And on the flip side, the more exclusive a gene pool becomes in order to reduce risk of unwanted traits, the more trouble you can run into.

:winkgrin: It’s fascinating isn’t it? :winkgrin:

Search for my thread re. Northern Dancer. :wink: I don’t get it either, because he was quite a horse apparently! But glad to know you heard the same thing I did… Phew, I feel less idiotic now! :lol:

[QUOTE=EquusMagnificus;5972631]
PF, can you provide me with the links explaining the AGR please?[/QUOTE]

Here are a couple from the other site. I’m not a scientist, so the underlying math is pretty much beyond me.

Here is a lay synopsis:

http://www.pedigreequery.com/forum/viewtopic.php?t=4185

Here is the study referenced in the synopsis:

http://cgil.uoguelph.ca/pub/6wcgalp/6wcMiller.pdf

Again, beyond my ken, but this appears to be a calculation model.

http://www.vsni.co.uk/software/asreml/htmlhelp/asreml/pedigree.htm

The calculation shows up regularly in scientific articles, but from what I’ve seen, not in the direct context of looking at the genetic impact of a specific ancestor. By their format, the TB and Allbreed linebreeding reports do suggest that AGR can and should be used in that way, however.

It varies by pedigree, but as an example, according to AGR Nearco and his sons Royal Charger and Nasrullah tend to pack a wallop in a pedigree and regularly have a significantly higher AGR than Blood %. Mahmoud and the Tudor-line horses (Owen Tudor/Tudor Minstrel) are similar, particularly Owen Tudor (but daddy Hyperion usually has an AGR near his blood %). Tourbillon rarely has any difference between blood % and AGR. As you get back further in time (horses born roughly before 1915) the trend goes the opposite direction – horses like Galopin, Swynford, St. Simon, etc. tend to have lower AGRs than blood percentage (suggesting diminished influence), even with double-digit crosses to those horses.

I am not finished with my research, but what becomes most striking about AGR is how it diminishes the presumed impact of the older “foundation” sporthorse reference horses – Bay Ronald, Dark Ronald, Galopin, etc. That is one of the main reasons why I want to understand it better.

Sorry for the rant. Been thinking about this too much.

I’ve been known to make faces about Northern Dancer, good as he often is. He comes with several factors that make him a bit dicey in breeding, and since we’ve seen thousands of his descendants, there is more to go by than with lesser prevalent lines. Grandson of Native Dancer, great grandson of Polynesian, and ggrandson of Sickle. This line is rather notorious for soundness issues, and has been even before Northern Dancer was foaled. He was basically a mini Native Dancer. Both horses were very heavily muscled, but ND was tall and No. D was much smaller. Family weakness seems to be ankles and tendons, per writers of the time. Both horses were prematurely retired from racing because their front legs couldn’t hold up to the stress that those heavy muscles put them under. What I call the Northern Dancer curse is a very heavy body on spindly underpinnings. They may still be fast and good racers, but they are less likely to stay sound. I’ve always heard tendons were the problem, and tendons can be “hardened” with the right training, but racing writer Charles Hatton talked about Native Dancer ankles.

[QUOTE=GGStables;5970444]
I’m studying pedigrees and pondering: Generally, how far back would one evaluate a bloodline in generations before it is too diluted to be significant?[/QUOTE]

me personally (not a scientist at all) I stay within three generations…which is not to say that the sixth generation cannot express itself in the animal (which I can only tell by photos and performance at that point)

but I prefer to deal with a pedigree in sets of three (three here and three there)

Tamara

[QUOTE=Equine Reproduction;5972439]
If you look at a pedigree where a stallion 5 generations back was a gray and you keep going forward, you stand a 50% chance (unless you breed to another gray) of the resulting offspring being gray. If the resulting offspring is gray, the next generation you still have that same opportunity. Some traits are multi-gene determined, such as height. And of course, with recessive traits - think a chestnut here - you can breed bay horse after bay horse after bay horse after bay horse, and suddenly end up with a chestnut horse! How’d that happen??? ;). How many times have you looked at a horse and thought WOW…he looks like his grandsire? Or great grandsire? [/QUOTE]

This made me think of my mare. She is a bay with a tiny white star like her damline, that’s it. Her FULL sibling is gray. Her sire is gray, and several generations of grandsires. I have wondered if that gray factor is what made her foal have SO much white on him - I had been expecting a minimally marked tobiano and got mostly white with a lot of roaning.
http://www.pedigreequery.com/flippedherhalo

Here is interesting articles–do not know how accurate they are – but it discusses, among other things, influences as far back as the 6th -10th generation and doubling up on stayers to make sprinters and using siblings etc.

http://www.sport-horse-breeder.com/american-thoroughbred.html
http://www.sport-horse-breeder.com/pedigree-generation-position.html

Bumping this back up. Warning - long post!

Anyone out there have any thoughts on whether the blood% of a distant ancestor in a pedigree has predictive value? I really do want to understand this better.

Here are my thoughts, for what ithey are worth:

To provide some perspective, the blood percentage of each ancestor in the 4th generation (16 horses) is 6.25%; 3.13% in the 5th (32 horses). Base upon what I am seeing from a pretty detailed review of linebreeding reports, even a heavily linebred distant ancestor is unlikely to have a blood % in excess of 6.25% – under this analysis, the blood equivalent of a single 4th generation ancestor.

As I understand it, each sire/dam contributes, on average, about half of the genetic makup of their offspring; in a linebreeding situation, one would expect different contributions of genes to revert to the mean to a large extent. Stallions and mares have to be considered equally. I believe that means that blood % (or perhaps better, AGR) can be used as a rough estimate of the level of influence an ancestor may have on the genes of a horse.

Applying that logic further, I would think that seeking only one “quality” sporthorse ancestor in the 4th generation (each horse at 6.25% influence) of a horse’s pedigree should not get us excited – even if that horse is Hyperion (or, to use a warmblood-breeding reference sire, Ladykiller). In that scenario, ~94% of your F1 horse’s genes likely come from other sources.

Instead, if you are going to breed an animal, you’d want to see that 4th generation literally packed with quality sporthorse ancestors. Every single one should count. At that point it seems to be a mistake to focus on specific sire (or dam) lines in the pedigree; instead, you are hoping that by stacking the deck in more distant generations, you’ll get something of quality in this one.

The complicating factor with Thoroughbreds is that they are not bred for sport, but for racing (duh!). For eventing, ancestor racing success (particularly in turf/NH scenarios), probably does indicate an aptitude for cross country – at least in terms of the overall athleticism, speed and stamina of the animal. For dressage and showjumping a connection between racing success and sport does not seem as clear. My guess is that warmblood breeding, done carefully, is likely to be more predictable for sport than using Thoroughbreds or native-breds, because even 4 generations back you are likely to get a densely-packed set of ancestors evaluated and bred for sport, or with Trakehners, for use in the military. And usually without a closed book.

The exception to this would be where a heritable trait is obviously and consistently being passed down over several generations – color being the most obvious yet least functional of these from a sporthorse perspective, but it could be other observable traits such as conformation and movement. It is easier to track through sire-lines simply because we usually have more information about stallions than mares. If you can show that Bay Ronald-Bayardo-Gainsborough-Hyperion-Owen Tudor-Tudor Minstrel-etc. were all good movers, and the other horses in the pedigree were not known as good movers, then you may have something solid to rely on.

As is probably obvious, I am more concerned about event breeding than anything else, and I am convinced that the thoroughbred will remain a necessary element for event breeding, and will continue to be used from time to time in the more warmblood-dominated sports. Not trying to be a kiss a$$, but this is why commentators like vineyridge and some others here are so important. She’s actually taken the time to understand and really try to find out the sport qualities of what are fundamentally racehorses, and not just the well-known ones. Most don’t have the time or inclination to do that kind of research.

Whew. All of this may be obvious or old news to a lot of people, but writing it down helps me collate my thoughts. :winkgrin:

So, to sum up what I think as to the predictive value of a pedigree based upon what I have reviewed so far:

  1. An ancestor, even linebred multiple times, is unlikely to overcome the more recent generations of a pedigree unless they have passed down a identifiable dominant trait that has weathered the storm of multiple generations.

  2. Unless it is in the first couple of generations, the predictive value of a single horse’s appearance in the pedigree is likely to be low.

  3. Because of this variability, for breeding purposes, the goal should be to have a breeding animal whose distant generations are packed with ancestors who have been identified as being of a “sport type” (in temperment, conformation and/or movement) or who are known to have produced those qualities in the breeding shed. This increases the chances that a sire/dam will also produce a quality sporthorse type.

  4. Other than looking at obvious conformation traits, it is more difficult to identify thoroughbred “sporthorse” ancestors that predict sport performance than in warmbloods, for example, because of the emphasis on racing success. This is probably less of an issue in eventing than in other discplines, so long as one focuses on racehorses successful at longer distances or over fences.

Add to it; poke holes in it – tell me where I’m wrong or the where the science does not support the conclusions. I post these missives not only to organize my own thoughts, but to solicit those of others as well.

Sorry again for the rant. PF

Genetics…oh so much fun.

Most genes work as an on or off situation, like computer code of base 2. However, most traits have multiple genes contributing to the overall phenotype. You must first understand the difference in Genotype and Phenotype. To put it simply phenotype are those genes that currently being expressed in the animal in front of you, and Genotype are those that are, and are not being expressed but are possessed by the individuals genetic code. Some like to look at Genotype as what genes that are carried by the individual, but aren’t necessarily expressed. So if you understand that, you will realize that a gene can be passed from generation to generation without ever being expressed. Then one generation, bam here it is. The gene isn’t diluted because of the number of generations that it remained dormant. It is just as potent as it was in the horse that first expressed it. Furthermore, some genes are only present via sex linked genes, but may be carried by the opposite sex. You don’t know until you see what the animal breeds. I can look at my foals and see who they garnered most of there genes from. Some genes tend to skip a generation or are only transferred via the mare or stallion only. Some are only expressed when matched with other genes.

You might think this leads to “Breeding is a Crap shoot” however I would suggest it isn’t. When we look to the children you will see what genes they are breeding with. When we look to the family, we will see who contributed them. Once you know what family members your mare is breeding with, you should be able to find a stallion that breeds with family members that jive. Breeding then becomes a practice of risk management and knowing what not to do. If you do this well, you will be successful.

Tim

To provide some perspective, the blood percentage of each ancestor in the 4th generation (16 horses) is 6.25%; 3.13% in the 5th (32 horses). Base upon what I am seeing from a pretty detailed review of linebreeding reports, even a heavily linebred distant ancestor is unlikely to have a blood % in excess of 6.25% – under this analysis, the blood equivalent of a single 4th generation ancestor.

I see the point you are making. I agree that, of course it is silly to get excited about just one “big name” horse 4 generations back. A pedigree should be “stacked” on both sides in order to improve the odds of success.

However, let’s use a very simple example to illustrate why line breeding can be somthing to get excited about. Say that a new discovery showed us that gene Z is super important to eventers’ ability to excel. Some years ago the stallion “Horsie” was popular for siring eventers, he was also homozygous for ZZ. Horsie is long dead now but we know that he passed on a Z to all of his offspring. As his get are bred to other horses that are Zz or zz, the likelihood is that by the 3rd or 4th generation you will see mostly Zz or zz. However, if you breed your mare to another one of Horsie’s offspring, you can hope that he too will be ZZ or Zz. You are increasing the likelihood of seeing this desirable trait, even though Horsie only contributed a small percent of your foal’s total genetic makeup.

I am no biology expert so I may have used the wrong terminology here at some point, but I think my message is valid.

I love the craziness of genetics. But it is not at all straight forward. One can’t say that at #X generation the influence is gone, because it never is.

To pick on color: I have a buckskin Swedish warmblood. Following her pedigree via her sire’s mareline starting 8 generations back and coming forwards to present day, I see 5 generations of grey mares all in a row. The most recent grey mare was bred to a bay stallion (his pedigree is straight bay, black, brown with 1 grey for good measure, top and bottom for at least 15 generations). The resulting filly (my mare’s grandmother) was buckskin. Go figure.

I always figured you needed a dilute parent to get a dilute kid, so this appears to be a throwback. So, I got curious and tried to trace it. I know for sure it came via the Swedish grey mareline (great-grandma). Grey Great-Grandmother’s damsire is listed as buckskin, but his color photographs show him as a black-bay or brown, so I’m personally not convinced he is a buckskin. But, if I follow the grey great-grandma sire-line, her great grandfather, born in 1932, is listed as “light bay”, so perhaps he actually might have been an unrecognized buckskin (that’s 6 generations back from my mare). Everyone else in his personal pedigree is listed as bay or chestnut.

Anyway, the buckskin SWB grandmother produced a buckskin stallion and he produced my buckskin SWB mare.

I’m no color guru and I don’t really study it, nor do I breed for color, but it’s just one example how you can’t really be certain that 5 or 8 generations back is enough to say that A, B, C or D genes are too far back to count, whether that be for temperament, movement, body type, color, whatever. For my mare’s grandmother to become a dilute, the dilute gene had to come from way back.

The genetic skeletons in the closet can come out at any time.

Others above explain it quite well. Sometimes something is suppressed and gets carried along until the right something turns it on and up it pops. This is very clear just from trying to trace the origin of my mare’s color (let alone her other characteristics).

So basically you’re saying the further back it is, the more reduced the influence so those don’t matter too much. (unless of course a total sum of the same stallion is more than (fill in the blank____ %) that makes sense.

Using my two mares: Which hypothetical pedigree is best in terms of ancestor placement in the pedigree? Forget about the names for this demonstration, I’m a visual type, I’m trying to get a feel for where the same names must appear for the most “bang for the buck” without being too too close. ***What IS too close of a line breeding?

% is the number of different ancestors in the first 6 generations.

IF a stallion is represented a couple of times in the first 6 gens, should you look further back to get his total influence %? For example, in the examples below, Grande shows up beyond the 6th gen. I would think that additional % of Grande could be a good or bad thing depending in what the goal is. *So you should get his total influence past the first 6 correct?

95% different
http://www.sporthorse-data.com/dbtestmating.php?&sireid=10469025&damid=10600394

92% different
http://www.sporthorse-data.com/dbtestmating.php?&sireid=76495&damid=10598869

81% different
http://www.sporthorse-data.com/dbtestmating.php?&sireid=10520901&damid=10598869

81% different
http://www.sporthorse-data.com/dbtestmating.php?&sireid=418975&damid=10600394

85% different
http://www.sporthorse-data.com/dbtestmating.php?&sireid=10741579&damid=10600394

Good points both TSH and Rodawn; I do understand that genes underlying a specific trait can be passed on and be dormant for several generations and then pop back up. To ask another question about your examples, however, if the linebreeding is way back in the pedigree, does it significantly increase the chance that a particular trait or bundle of traits will pop up now? My guess is probably not.

As I see it, pedigree analysis is fundamentally about trying to make an informed decision as to whether to breed two horses based upon their ancestry (putting aside their observable phenotypes for a moment). For purposes of trying to increase predictability in breeding, is it wise to put one’s eggs in the basket of a distant linebred ancestor? Most times the answer is probably no, but it is great to have them back there in case you get something spectacular from way back, and that is probably more likely than in a warmblood breeding scenario because TBs are a closed book.

I am a big fan of consolidating specific bloodlines and reinforcing them in carefully planned breedings…but that’s just because there is a definite “type” I like to ride. It also takes too long to train a GP horse to add in dramatic changes (i.e. huge outcrosses) that will require a ‘new’ system or equipment changes in the training program. Add in longevity, soundness and the mind…well, it is possible IMO in warmbloods (or any breeding program really) but you have to do your homework and know exactly what characteristics you might reinforce (good or bad) and be prepared to work with the results.

There are a few COTHers that have come to the farm over the years and we all have a good laugh about how it is absolutely obvious who is related to this guy and who isn’t… :slight_smile: They’re clearly stamped by him - just sometimes in different wrappers and sizes but that gives into geno/phenotype expression discussion. IMO there are certain characteristics (behavior, rideability, movement) that are color- or sex-linked but that’s just MO…fwiw.

[QUOTE=Peregrine Farm;5975898]
Good points both TSH and Rodawn; I do understand that genes underlying a specific trait can be passed on and be dormant for several generations and then pop back up. To ask another question about your examples, however, if the linebreeding is way back in the pedigree, does it significantly increase the chance that a particular trait or bundle of traits will pop up now? My guess is probably not.

As I see it, pedigree analysis is fundamentally about trying to make an informed decision as to whether to breed two horses based upon their ancestry (putting aside their observable phenotypes for a moment). For purposes of trying to increase predictability in breeding, is it wise to put one’s eggs in the basket of a distant linebred ancestor? Most times the answer is probably no, but it is great to have them back there in case you get something spectacular from way back, and that is probably more likely than in a warmblood breeding scenario because TBs are a closed book.[/QUOTE]

:yes:^^
Also, if some genetic traits are dormant but can pop up at any time, then how can one tell from any amount of research what traits they are unless the pedigree pairing has produced literally 1000’s of foals?

Conversely, if we kept using only proven nicks regardless of what pops up every now and then, then virtually every horse bred from that pairing should be superior (which we know is not the case and my crapshoot comment is in this context) and we’d be well on our way to having inbreeding problems associated with an essentially select or ‘next-to-closed’ genepool.

I keep going back to Fidelio du Donjon, a current 97% or so SF stallion. He’s only got a touch of non-TB, but of the TBs in his pedigree, he has over 19% Blandford–and Blandford was born in 1913 or thereabouts. Bred to a mare who carries several different lines of Blandford, you keep the dilution in the next generation down to a point where you will still have significant effect from that line.

I know I’ve seen his Blandford percent this high. SHBD only has Blandford at just over 10%–still high, but not shockingly so.I agree with Peregine Farms that packing a pedigree with ancestors who have been well proven to have produced for sport increases the chances that whatever genes you do get may get will have a 50% chance of being expressed.

Unless I’m figuring the numbers wrong, each parent provides 50% of the genes and there is still only a 50% chance that that 50% will be expressed. Given multifactorial (don’t you love that jargon) genetic traits and epigenetics, the amount of potential variation is staggeringly high.

Some of Nothern Dancer’s direct offspring:
http://www.sporthorse-data.com/horse/10010331/329/Horse_Adbass-big.jpg
http://www.pedigreequery.com/photos/DANCEINTIME.jpg
http://www.sporthorse-data.com/horse/10036747/122/Horse_Danzatore-big.jpg
http://www.pedigreequery.com/photos/ELGRANSENOR.jpg
http://www.pedigreequery.com/photos/ESKIMO.jpg
http://www.sporthorse-data.com/horse/499500/980/Horse_Glenstal-big.jpg
http://www.sporthorse-data.com/horse/10056461/790/Horse_Heros_Honor-big.jpg
http://static.flickr.com/133/322177986_e10739a702.jpg?v=0
http://www.ziprickthoroughbreds.com/luckynorth.jpg
http://photos-c.ak.fbcdn.net/photos-ak-sf2p/v644/239/121/1114583270/n1114583270_242226_9946.jpg
http://www.sporthorse-data.com/horse/10134206/420/Horse_Razeen-big.jpg
http://www.pedigreequery.com/photos/WARRSHAN.jpg

[QUOTE=Equine Reproduction;5972439]
Think color for example. If you look at a pedigree where a stallion 5 generations back was a gray and you keep going forward, you stand a 50% chance (unless you breed to another gray) of the resulting offspring being gray. If the resulting offspring is gray, the next generation you still have that same opportunity. [/QUOTE]

Don’t mean to derail the thread but I thought that there were only a couple definites in color. Chestnut to chestnut = chestnut. To produce a gray offspring, one of the parents needs to be gray. You’re saying that you could produce a gray 5 generations later out of non-gray parents? Really?

Love this forum … learn something every day!

Thanks!!

[QUOTE=vineyridge;5976683]
… Given multifactorial (don’t you love that jargon) genetic traits and epigenetics, the amount of potential variation is staggeringly high.[/QUOTE]

That pretty much sews up my thoughts in a neat sentence.

No. You cannot get a gray offspring by 2 non gray parents. You can however get a non-gray offspring when they have 2 non-homozygous gray parents.