Not all horses respond adequately to 1 ml dose. My mare is now moving to 1.25 ml every 10 days. She was on 3 tabs of Prascend, that had to be dissolved and syringed to her to assure she got them. She was constantly off feed with daily medication, so we moved to the shot. 1 ml got her ACTH numbers down to 50. Being lethargic and off feed is called “veil”.
If you notice a “veil” after giving medication (either prascend or cabergoline) you might try adding up to 10 ml daily of a product called APF. Advanced Performance Formula helps with this. The label says 8 ml for metabolic horses, but my delicate flower does better with 10 ml and still has 2 off days after every injection. Per Kellon’s advice, I give the APF two days before her shot and continue for two days following. Kellon feels this gives the same benefit as continuous dosing of this supplement. Becca hates this too, so I syringe 5 ml morning and night, which seems to be more acceptable for her. The struggle is real. And costly with regular blood work to Cornell for monitoring. But she’s worth it!