In 2011, majority of my competitions and training were in Area 2. I only did the seacoast (95) once and it was a nightmare. Not really bad traffic, but the construction zones were endless.
I usually take I84 through MA and CT to 84 (towards Hartford, CT), then hook on to I 81 (to Harrisburg PA) right down south. To get to Aiken, I think you can hook up to I 77.
For Southern Pines, it is a difference of about 1.5 hours and 90 miles. But, NO tolls and rarely any traffic. Lots of 18 wheelers, very little rural traffic. So, traffic keeps moving consistently - not many accidents and it is an easy drive.