OP
Just wanted to say sorry for what you and your mare are going through .
I think exploratory surgery might be the way to go, but it is a decision only you can make.
Just a suggestion, but you may want to consider getting a consultation with the local county extension office.
Your mare may be eating a seasonal grass , plant or weed that she is highly allergic to.
This plant dies off or mostly dies off during the cold months which could explain why her symptoms improve at that time .
It is an onerous task to try and pin point just what plant it might be. But it may be worth it to try.
Hay could also be a problem. And a lot harder to trace, as hay can come from so many regions.
Good luck. I hope you can finally get an answer.