Esomeprazole (Nexium) for equine ulcers

Yes yes! I was posting more as a discussion question type thing!

Thatā€™s very interesting. Touch wood, my horses donā€™t seem to need any additional gastric support at this time. Iā€™m the ulcery one evidently :woman_facepalming:t2:

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Are you guys feeding the capsules on a completely empty stomach (like, before morning hay)? Iā€™m starting my horse on the Nexium regimen this week. I can feed 1 he after morning hay, before any grain, but canā€™t get to the barn early enough to administer before hay. Please share the protocols that youā€™ve used, thanks!

No, I fed them on top of grain with pm feed.

Given how my barn runs, my horses arenā€™t eating much hay prior to that time as theyā€™re milling about waiting to come inside.

I have mine in the tail end of a batch right now (with really good results). I just put the capsules on top of his grain & he eats them.

@wildlifer, is that in the morning or evening?

Iā€™m doing that in evenings.

Has anyone scoped after Nexium Treatment?

Would the three 20mg pills be a good dose then?

Going through the same symptoms with a new mare we got at my barn
Pinning ears back, trying to bite , when leg pressure ,so we are not able to ride her. She has been scoped and showed ulcers , we are starting third week on gastrogard ,
This is my first experience with this problem .
She had been being giving a product call gastric plex ( acts like a human tums) she had none of these symptoms , we quit giving this to her because you had to give in empty stomach and the schedule it was pretty impossible to do that.
Then she became a witch! This scoping etcā€¦.

Thai same company that had this gastrigard product I called and they told
Me they have a better product that actually helps with the acid and prevents ulcers , pellets you put in feed . The price was very reasonable so Iā€™m thinking about ordering this after the 30 days in gastrogard

I know several have, and pretty sure they posted in this thread. Maybe search ā€œscopeā€ in this thread and see if you can find them?

For an average 1100lb horse, yes. Is it guaranteed to be a high enough dose? No. But itā€™s a place to start. Lots and lots of horses seem to be helped by that.

What product?

GastroGard and UlcerGard are made by Merial. I donā€™t know of any pelleted product approved for preventing ulcers, whereas UlcerGard is (and itā€™s a paste)

Made med -Vet pharmaceuticals 8003668986 you would have to call I believe the pellets are for horses who have been treated and then this is a preventative ,
They are who also have paste called gastroplex , the gastriplex consist of probiotics and a couple of amino acids , things that a good diet should give a horse
I know one thing we quit giving this mare it and after threes weeks a huge difference in her temperament ( biting, kicking out, pinning ears back, pretty much unridable , she does all this when you put your leg in her to ask for a trot ,
She has been scoped and we have had her in gastrogard and have two more wks To make 30 days , sure hope it helps!
I will be giving her a preventive product and will try the pellets you put in feed that they have and I was told that itā€™s better than the tube of gastrplex they sell

The point actually is, unless itā€™s an approved drug, they cannot claim it will prevent. You canā€™t do that with supplements.

Not a Nexium post but after a year of ulcer hell with my young TBā€¦ multiple scopes, 3 months of GG, 4 months of Misoprostol and Sucralfateā€¦ I think weā€™re finally on the right track.

An unexpected barn switch may have been a blessing in disguise for us. Transitioning to a different facility seems to have made all the difference. Heā€™s still on a maintenance dose of Abler, but weā€™re seeing progress that we didnā€™t even when he was on that whole cocktail of meds, turned out 24/7 with friends and out of work for most of last spring/summer (aka the best management we could offer at our previous facility). Weā€™re hopeful that we might be able to wean him off completely over the next couple of months. Heā€™s back in full work and getting better and better week by week.

Mostly just sharing because I know people here can appreciate the struggle.

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@Simkie @JB

I started a separate thread, but wanted to get the opinion of the resident COTH experts. Due to boarding barn constraints, I am only able to give Nexium in AM/PM feed. My horse has been on AM/PM sucralfate for 2 weeks. I am not able to give the Nexium reliably before either feed. My options are to add Nexium with the sucralfate and hope it gets absorbed or to add Nexium to AM feed and only feed sucralfate at pm feed.

Question - does the Nexium get absorbed in the intestines, and if so, would the sucralfate still block absorption? Which option do you recommend I go with?

Sucralfate needs to be dosed away from other meds byā€¦what, at least an hour? Iā€™d definitely not dose them together. I donā€™t think using sucralfate once a day is enough.

Can you pay the barn, or another boarder, to give your horse a handful of grain at lunch with the Nexium? Or are you there every day, and can give it away from the sucralfate?

Do you think the sucralfate is helping? Another option would be to drop it entirely.

I am so happy to have found this thread. I read everything carefully and bought some generic esomeprazole on Amazon. My horse was dosed at 60 mg/day (3 capsules). He seemed improved after 4 days, so I kept him on the dosage. About 3 weeks after I started, he got a hoof abscess in his left fore. Right after that straightened out, he got one in his right fore. He got some bute, too, during the left fore abscess, so I upped the esomeprazole dosage to 4 capsules (80 mg) and went back to 60 mg a few days after I stopped the bute. I ended up keeping him on treatment dosage of esomeprazole for 8 weeksā€“longer than this thread has recommended. But I had to move him from a stall/run to an indoor box stall, which was stressful for him.

With the tapering-off, he was on esomeprazole for 11 weeks. Itā€™s been a month since I ended the dosage and he is soft-eyed and happy. My vet commented that his stomach seemed a bit ā€˜hyperactiveā€™ but liked my ulcer prevention protocol. I am hoping that 3 lbs of alfalfa pellets throughout the day, 3-5 servings of Purina Outlast, G.U.T. and Succeed will help keep him ulcer-free. I will discontinue the Succeed in a few weeks after supplementing with it for 3 months. I was also pleased that my horse had a zero fecal egg count, all types. Iā€™ve learned a lot from otherā€™s experiences here, so thought I would share. Any suggestions or observations are welcome.

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Are you feeding your alfalfa pellets dry or wet? I always thought dry would be the easiest way but not sure if it is the best way.

Well, here I am treating a raging case of ulcers (not scoped but presumed) in a horse that was away at the trainers for 4 months and got home 2 weeks ago. He tapered off his grain and was girthy. This horse ALWAYS eats his grain so we are on 3 weeks of GG then going to start the Nexium route. He is 1325 pounds so thinking 3 or 4 (?). What should I use for hindgut? EquiShure?

CindyCRNA, I feed them dry. Itā€™s easier, plus I keep a salt block in the pellet bucket so wet is not a great idea. Someone else I know soaks her pellets. My horse is outside in a stall/run, and soaking runs the risk of feed freezing in the bucket in winter. The one who soaks is in a heated barn.

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