I’m sorry about your horse, I hope she pulls through. EPM is a horrible disease; I wouldn’t wish it on my worst enemy. :no:
I don’t know about this experimental medication but with Marquis it isn’t unusual for them to get worse after beginning treatment as the protozoa start to die off. If you are able to get her on her feet and you may be able to get her through this beginning phase.
Huh. That’s sweet. I hope your horse pulls through and that you never have to deal with this disease again. :no:
[QUOTE=Domino’spal;6203888]
Well…just an update…she is down and cannot get up. I even had the fire department out. Not looking good. Thanks for all the support! Hope it happens to you someday. . Karma.[/QUOTE]
Whoa! I was totally understanding of your emotional and slightly irrational (for your level of education) posts given your situation with a sick horse until I got to this post. This is really over the line. Nobody was wishing your horse do poorly, but there are skeptics about whether you are “real” or not. Like anything else that lacks double blind studies, it send a goup of people on this board into a frenzy. You just got caught in the middle.
I hope your horse makes it!
And just curious, what did the fire department do?
Tried to get her up and standing. At which point, I was going to sling her in hopes this med. Would work. Not looking good. She is exhausted.
Well bless your heart!
There’s been no frenzy here. And, while I believe the OP’s “hex” on the rest of us was uncalled for, I still wish her and her horse well.
How did the FD try to get her up?
For any horse owners reading and hoping for a miracle for their own EPM horse(s), the percentages above are not only improbable, but impossible. I know for a fact that horses that don’t respond to O-10 are designated as having a problem other than EPM and are removed from the “trial”, so negative results are not factored in. That said, there’s no way that 96% or horses with EPM that have been treated with this stuff (or any stuff) could be “completely healed”. EPM is a nasty and pervasive disease and there will always be a percentage of horses with irreversible neurological tissue damage. :no:
Jingles for your horse. To change the tone of the thread the OP can edit the first post and title - i.e. asking for jingles WILL receive sympathy and support.
May the worst be behind you.
OP, jingles for your mare. EPM is an awful disease to deal with.
I have also used the Pathogenes treatment for an EPM horse and have been satisfied with the results so far. FWIW, they did warn (via my vet) that the horse’s symptoms may become even more acute within 48 hours of starting treatment, due to protozoal die-off.
And for those concerned about Pathogenes charging for an “unapproved medication” - I do not believe any funds go to Pathogenes for the meds. In fact, the results sheets sent to my vet contain the Franck’s phone number, and his previous interactions with Pathogenes directed him to order the meds directly from Franck’s - which is what he did.
Also wanted to state that I do not believe Pathogenes claims a high percentage as “completely healed”, but rather their results so far show a high percentage with significantly reduced titers and symptoms after treatment with Oroquin-10.
I have another horse that recently tested fairly high for all three SAG phenotypes, but she currently exhibits no symptoms, so the Pathogenes recommendation was to not treat at this time and retest in a few weeks.
jingles for your mare
Thanks for the real time information Downyonder on how it worked on your horses.
As many did suggest the OP was a paid promoter I can see she/he may have been offended as it seems like she /he was more likely an concerned maybe over enthused (?) owner.
And Jackie Blue --why so rough on OP – I do not think she/he is selling the product. In contrast, at one time you sold the dynasplint (apologizes if I am wrong) but that sure was hyped to be a cure all for any and all deformities. I dont think you ever received such a grilling and you were actually selling it.
Wow, omare. First, I don’t believe I was hard on the OP. I questioned her statement that she was an epidemiologist b/c she positioned that fact as reason to follow her example of using Oroquin-10 and because she was clearly unconcerned with the usual scientific method. Was I rougher than any other scientific-minded poster?
As for the Dynasplint thing, not only did I work for Dynasplint, I pioneered the use of dynamic splints for angular and flexural deformities and managed the Veterinary Division. Dynasplints are CHAP accredited, but being medical devices, not pharmaceuticals, they are not eligible for the same sort of FDA approval as commonly used medications.
Regardless what the company claims now, I never touted the splints as any sort of panacea. As you can dig up if you’d like, I’ve posted on many limb deformity threads here. If I didn’t think splinting would help, I said so. Many people I’ve splinted for are on this BB and I think they’d all agree that I know the limitations and risks of splinting horses and also that I know of what I speak when it comes to flexural and angular limb deformities. I don’t think you’ll find a thread started by me stating, “Great News! NEW Magical Leg Fixer!”
I don’t know how my previous affiliation with Dynasplint really has anything to do with a thread about an experimental drug cocktail, but I hope I’ve answered your questions. 
Challenging miraculous claims, demanding evidence, and being skeptical of research practices that do not seem up to snuff is NOT PERSONAL. Those who TAKE it personally have an inappropriate emotional relationship with the product, method, disease, or practice being questioned. There’s plenty of room for passion and emotion in science, but investing in results personally is perilous. Data don’t always come out the way we like, and promising “cures” don’t always work, much to our collective dismay. The scientific mind that wishes to remain sane invests emotionally in the PROCESS, not the RESULTS.
Just an update: At 4 o’clock she got up! The meds came and hoping for good results. I think we all want our horses to get well sooner! I am hoping this to be the case. Pics on fb of the horse downtown with FD. For all disbelieving.
So glad your girl got up, although your tone is disappointing. Who questioned that your horse was down? I questioned under what name your studies were published. You never answered. It’s not a personal thing, just fact finding. I offered and continue to offer sincere sympathy and positive thoughts for your mare. Not sure why you feel you’re being picked on.
Again, glad she’s up. :yes:
[QUOTE=Domino’spal;6206460]
Just an update: At 4 o’clock she got up! The meds came and hoping for good results. I think we all want our horses to get well sooner! I am hoping this to be the case. Pics on fb of the horse downtown with FD. For all disbelieving.[/QUOTE]
So either I’m a dummy or there is a facebook page in some other name…searched farm name and owner name on FB and got nothing…
The FB page has apparently been taken down. I saw it last night.
My page is up! Fastfirstfarm Emma is still with us and seems more alert. She is eating hay and apple treats. No grain yet by her choice. Pathogens DID warn me about her doing worse before better.
As someone who did not know about this new drug, I was excited to share in case others were in the same boat.
I DO NOT need to justify my credentials with anybody. This was not what this was about. I do love stuff to do with disease. And I continue to work in my field of expertise…Infectious disease in humans!
This is why I was excited to share.
I will let you know how she does.I just don’t get why there is such hostility towards something that has the potential to heal horses way more cheaply!
All skepticism will dissolve when solid, properly gathered data are published. Skepticism =/= hostility. Your skin is awfully thin for a scientist. Glad the mare is perking up, though!
Her science is awfully thin for a scientist…
