My vet told me there was a new drug out there that’s suppose to be an alternative to TILDREN but without some of the negative side effects (Calcium).
Does anyone know the name or have any experiences with it?
I think it is Osphos.
http://hoofcare.blogspot.com/2014/07/navicular-syndrome-does-fda-approval-tildren-osphos.html
It just so happens I was on hold waiting for my vet at New Bolton to pick up to discuss Tildren, killing time on CoTH and saw your thread.
Osphos made by or distributed by Dechra Vet Products is the alternative.
In the process of deciding on which to go with on a horse. Yes, Tildren has some negative side effects associated with it. But it seems more horse are good with it then those that are not. The same can be said of Chemo with humans. We only hear from those with horses who did not tolerate it well.
Osphos is relatively new from what I understand but bascily works on the same principles at Tildren. As to which is more effective the jury is still out. So we owners are going to be paying to be guinea pigs for a while. Like a lot of horse “treatments”.
Many horse meds come from human applications. Tildren being one. Maybe because Osphos is Tildren “based” but made for use in horses it may in the end be a the better product for horses.
Both are now FDA approved so it can be bought domestically in the near future. Tildren cost close to $1,000 per treatment because it had to be imported from France and only to vets with a license to import. The price is supposed to drop to around $500. Been playing the waiting game since the end of July. Our vets in 2 states were told it would be available by the middle of August, now they are being told sometime in September. Very frustrating.
That’s it. Osphos (clodronate injection)
Im in the same boat. Want to try one but so many factors to consider.
I’m tied of making decisions. When you have let me know and I will go with the same.
Just got a message from my Vet in Maryland that due to some hold ups by the FDA Tildren will not be available “domestically” until possibly November. But of course it can still be special ordered/imported and used but at the “import price” of $1,000. Checking to see if it is the same for Osphos.
With all the things the FDA has to concern themselves with and they have to make “rocket science” out of this. It’s not like it is coming from some third world country. And has been used in this country for a while now. Gees
Does make one wonder if the vets that have the import in stock are playing games to unload the “expensive” stock before the price drops by 50%.
Was just told that Osphos is only in “trial” stage at this time. So supply is very limited.
So, there would be very few people in this country with any long term experience at this time.
So that made the decision easy. I’ll go with what is available and seems to be of value. I heard very good things about Tildred. No direct worries about side effects only what I have read.
My local vet also said Tildren is not readily available right now. Haven’t checked with the University.
We are just now adjusting shoes to wedged eggbar. I want to try one thing at a time to see what works and what doesn’t.
Sounds like Tildren is our best bet once available.
Update: Vet administered Osphos today. No adverse reactions except minor agitation over 15-20 min. period.
Any updates on the results of treatment so far?
Well, she’s probably just at the 50 day mark, which is where I was told I’d see a difference or not. The ground and footing have been quite favorable lately. I haven’t noticed her being off at all but haven’t jumped her lately either. It seemed to bother her more at the canter and while jumping, causing a shorter stride.
So unfortunately my answer is “maybe”? Nothing noticeably better but nothing worse. I’ll have to pay a little more attention to her and report back.
Thanks for the update. I’m watching with great interest … anyone else have recent Tildren or Osphos feedback?
Bump for this thread? Just tried Osphos for my guy and looking to see if it makes a difference
I did not have any luck with Osphos, but with a navicular bone spur it was essentially just a last ditch effort to make my guy sound enough to ride. It was easy to administer, and I know others have had good results. Good luck to others with problems more amenable to the treatment.
Updates, anyone?
Yes! I did get osphos right after my post and I do think it has been helpful with my horses sore feet caused by a cyst on the navicular bone and other stuff. He is 15 and although I don’t push him as much he seems to be serviceable sound to do lower level eventing. I was told that you need to get it redone every six months but that would put me close to winter so I might just wait till spring and get it done. Paid 450.00 for the shots.
Had osphos done on our 21yr old with mild arthritis about 3 weeks ago. He feels better than ever actually. Happy to go forward without a crop and off the leg more. Had no adverse effects. Checked bw after also because he did have renal failure years ago before we had him and all was well. So far I’m happy
Btw my guy doesn’t have navicular and this was just a shot in the dark because with the renal failure he really doesn’t need NSAIDs so trying what we can to help keep the arthritis mild for as long as possible and him happy and comfortable. He was also never lame just slow
My first round did show improvement. I should have done it this spring again but she’s been sound so I sort of forgot about it. Unfortunately she told me she needed another dose at a show recently. I just had it administered again last week.
I had Osphos injected in my 18 year old QH (ex reiner, 2nd/3rd level dressage horse). He has bone on bone arthritis in both hocks (the right in the worst though), a club front foot, and was starting to show intermittent front end lameness. The injection was this spring (I believe in May) and after two months I saw significant improvement. At this point he’s going much, much better than before the shot. Of course to put it in context, I mostly use him as a school horse for beginning dressage riders so he’s not being asked to do a whole lot more than W/T/C and a little lateral work. I don’t think he’d hold up for 2nd level stuff these days. 
What has everyone been paying for Osphos? I’ve seen it online (with prescription of course) in the $200-$300 range, but of course that doesn’t include your vet administering it.
My 13yo mare was just diagnosed with mild navicular, she’s sound on good footing, just would like to slow the process down.
