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Paralysis type incidents in 15 week old puppy-ideas?

A friend has a young pup that has had two “spells” of what seems to be a partial paralysis, first of her hind end and then of all four legs. It’s beyond the vets here in our rural town; they immediately referred her to a neurology specialist four hours away that quoted her $4500 for diagnostics. Friend is trying to figure out how to manage that expense, she is young and that cost is significant for her, understandably.

Pup is a mini-heeler, female. She has had two vaccination series with her third due on Monday which the vet delayed due to the spells, as I’ll call them. I’ll include some quotes of a text conversation I had with the owner relaying what the vets (two from the same clinic):

“Her heart is healthy, temperature is good, her head/neck and tail muscles never stopped working, she ate and drank just fine, she could still go potty although it was difficult so she would hold it a long time, they said no paralysis because her muscles worked good, and this has happened twice with no pattern and no warning. She hasn’t gotten into anything I can think of, no ticks, no bites, not diabetic, not hip dysplasia because her front legs will go out too at its peak.”

" The first time it happened in the afternoon, slowly she had her back legs get weak and by that evening she could barely hold herself up with her front legs. In the morning she was running and playing like nothing had ever happened and that’s how she was until five days ago when she woke up and I let her out of her kennel, she was already kind of stomping her back feet just a tad, and she was very tired but basically the same until like 7pm it started getting worse and worse and she couldn’t walk but that evening or even hold herself up with her front legs at all. No pain seemingly at all, not disoriented but maybe just a tad confused why her body isn’t doing what she tells it to. She has has her first two vaccinations but her third was meant to be today and we moved it to Monday to give her a little more recovery time with this thing.

“The odd part is that one started in the afternoon and could have been from all three things they think but the most recent one started after she was in the kennel overnight.” (I had asked her if they coincided with heat, exertion, or day/night)

The spells come on gradually and recede, the first one went away over night but the second one lasted longer, over a couple days. She sent me several videos, in the first spell she seems to plop walk her hind legs and get spraddled but the front end works fine. In the second spell she army crawls with her front legs and frog swims with her hinds but can’t stand. She can eat/drink/pee/poo without problem and is bright, alert, wants to play, normal puppy behavior other than the weakness.

I don’t think the vet did any diagnostics other than a basic exam; I asked about x-ray and the vets didn’t b/c they wouldn’t be able to see any spinal issues with it. Tick was ruled out apparently b/c nobody saw a tick. They didn’t prescribe anything for her, medical or for care; just referred her which was cost prohibitive right out of the gate. Pup is never unattended; she is in a kennel while they are at work and in a fenced yard with another dog, not taken around to a lot of random places or visits.

This is a small town with very limited vet care; the vet she’s been taking her to is an hour away as it is. We don’t have emergency care closer than two hours away; she knows she will have to travel to get the diagnosis/care that she needs. She’s getting a lot of random advice like chiro, essential oils, etc yeesh.

Does anyone have any ideas in the meantime? WWYD? They need to see a vet obviously but they literally went from local cow vet level to referred to the vet school in Pullman, WA. Escalated quickly. TIA!

Is she running and ducking under furniture in play?

I had a dog who’s “spot” was under a heavy wing back chair. As he got bigger, that spot got tighter. He would run and play and duck under the chair as his home base. Once, he ran and didn’t duck quite enough and just NAILED his back on the edge of the chair…and developed some pretty serious neuro symptoms in his back end. It all resolved pretty quickly with a round of steroids, but we blocked off the chair and it never happened again. Trauma from whacking themselves can cause swelling along the spinal cord & neuro symptoms until the swelling goes down.

Just one thing to consider that could absolutely cause this sort of presentation of “nothing wrong” at the vet but intermittent neuro deficiency at home.

Extremely possible! I was concerned about rough-housing in general but that is a variation that could easily be happening; I will mention it to her right now.

Has the puppy been given any flea/tick drops or baths w/ insecticidal ingredients?
Has the premises recently been treated for any vermin or insects?
Puppies lick and eat all kinds of things. I lost one years ago from licking up antifreeze/coolant
that dripped on the garage floor.

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Seizures? I know a dog that has strange movements like that but she’s on medication so it’s very infrequent and the episodes don’t last long.

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Myasthenia Gravis? It’s not typical for it to preset as only limb weakness, but possible. I’d be keeping a really close eye out for any breathing or swallowing problems in a dog with an undiagnosed neuro issue, aspiration is a devastating complication.

I’d be putting that pup on doxy so quick. Several of the dog owners in my general area that I connected with over Lyme had pups with paralysis type spells. One in particular had similar spells to what you describe. I think that pup had to have two rounds of doxy plus two rounds of prednisone. Pup didn’t test positive until the third blood draw.

My own dog tested negative twice, but miraculously a round of doxycycline cleared her up. She had fevers.

Hell, I’m half ready to put myself on doxy, but that’s another story.

It seems odd that no diagnostics were run at all though? Did I miss something.

At any rate, $4500 is a steep number. I’m afraid I wouldn’t be able to justify that price. And would be pushing for trying some more affordable options first

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All good thoughts, I’ve been brainstorming with her about something she could have gotten into or anything growing in the yard, new treats, cleaners, anything, totally throwing it all out there and I’ll throw these ideas too.

I was surprised that they didn’t give her anything at all too, not even a bring-her-back-if or watch-out-for, especially knowing they basically sent her into oblivion with the referral. I would want her on doxy too (and I’ve read your story and understand why you might want it too and hell, maybe I should too now that I think of it).

No diagnostics, at all. I’m going to encourage her to go to a next-level vet that can perhaps narrow things down at least, or be more involved with the current situation.

I truly appreciate any and all thoughts and will relay them all to her. She is doing as much research as she can in the hope of stopping any further episodes and/or having informed conversations with the next vet.

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Another thing to add to the list is a liver shunt. There are some tests (cbc/chem, urinalysis, bile acid test) that can be run as rule-outs…

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Doxy for everyone.

I will jingle for your friend’s pupster. She must be distraught with worry.

I like your idea of maybe a next level vet but not the $4500 to get started vet.

I was just going to say do some diagnostics to rule out a liver shunt. Years ago a Pomeranian pup I had started exhibiting weakness/spells. It was that.

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Your vet should be able to run basic blood and urine. Liver shut suggestion was valid. Basic spine xrays to rule out abnormality like hemivertibra. Consider wobblers. I would do these before specialist

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We had a pup who had seizures after vaccination. Twice. No one knew why. But he never had them again. Never had any more vaccinations either. Related??? Maybe.