They are again shipping to VA. I just received mine, today. 
[QUOTE=Lambee;7744431]
I have devoured this thread - read every post - WHY HAVE I NOT HEARD OF THIS BEFORE??? I retired my best trail horse due to arthritis in his hocks and navicular changes - I just texted my vet and she said she loves the stuff - she sells it for $145 for the 50ml (so no getting a script for it) and is bringing to me on Friday!!! I miss my old friend and am sooo excited to see if this will help him. Heās been on Previcox and was at my gfās rescue since the spring as a little kids lesson horse - which he loved - but heās loosing weight and I want him off the NASID. Thank you all for posting about your experiences!!! Iām a COTH fan for sure now!!![/QUOTE]
Lambee, you can order directly from Wedgewood for $119 plus $10 shipping, though I totally understand if youāre willing to pay a bit more to ensure that the vet/client relationship runs smoothly!
[QUOTE=Lambee;7744431]
I have devoured this thread - read every post - WHY HAVE I NOT HEARD OF THIS BEFORE??? I retired my best trail horse due to arthritis in his hocks and navicular changes - I just texted my vet and she said she loves the stuff - she sells it for $145 for the 50ml (so no getting a script for it) and is bringing to me on Friday!!! I miss my old friend and am sooo excited to see if this will help him. Heās been on Previcox and was at my gfās rescue since the spring as a little kids lesson horse - which he loved - but heās loosing weight and I want him off the NASID. Thank you all for posting about your experiences!!! Iām a COTH fan for sure now!!![/QUOTE]
Good luck! Iām not sure if It will do anything for navicular but itās worth a try.
So just when I think my prayers were answered, Iām confused again. For the last year Iāve done a TON of reading on Pentosan vs Adequan. I really am leaning toward Pentosan because of the feedback of others and the cost factor. My vet would not give a script for it though and then Adequan was not available. UGhH!
So I have a new Vet and YES! They will prescribe me Pentosanā¦but they told me there is no loading dose, just give 5ccās a week, every week. I have never heard this method beforeā¦plus my horse is about 1200lbs. I thought for sure Iād give 6ccās. Has anyone given a horse of that size just 5ccās and it work? My horse is an OTTB with 64 races in his past and about 14 yrs old now. What do you think? Everyone I see on here is giving the 6ccās. I also canāt imagine giving it weekly, my thoughts were- loading dose of 6ccās weekly, for 4 wks. Then 6ccās every 2-4 wks thereafter.
[QUOTE=wishnwell;7788789]
So just when I think my prayers were answered, Iām confused again. For the last year Iāve done a TON of reading on Pentosan vs Adequan. I really am leaning toward Pentosan because of the feedback of others and the cost factor. My vet would not give a script for it though and then Adequan was not available. UGhH!
So I have a new Vet and YES! They will prescribe me Pentosanā¦but they told me there is no loading dose, just give 5ccās a week, every week. I have never heard this method beforeā¦plus my horse is about 1200lbs. I thought for sure Iād give 6ccās. Has anyone given a horse of that size just 5ccās and it work? My horse is an OTTB with 64 races in his past and about 14 yrs old now. What do you think? Everyone I see on here is giving the 6ccās. I also canāt imagine giving it weekly, my thoughts were- loading dose of 6ccās weekly, for 4 wks. Then 6ccās every 2-4 wks thereafter.[/QUOTE]
Well, one thing is that you have to make sure you are talking the same concentration ā what I am using, and the āstandardā I think, is 250 mg/ml ā and with that, I give 6 cc. I donāt know if it varies based on size of horse as my little guy (15.3 and maybe 1,150 lbs.) gets same as the big guy (16.3 and 1,350 lbs.). I have used the loading dose of 6 cc every 4 days for 4 doses, then go monthly. Some people found they had better results going every two weeks after the loading dose. Iāve heard other vets use a different loading dose protocol, a series of 4 shots given once a week, but Iām not sure why the instructions differ. Iām just following the direction from my vet, and it seemed to do well for my guys.
So what exactly would my question to the vet be to verify the amount heād be getting per dose?
I got my Pentosan in today for the first time, shipped from Wedgewood. I havenāt started my horse on it yet because I have questions first. I have the usual bottle of 250 mg/ml formulation in a 100 ml bottle. When I did my math, after loading dose and 2x month injections thereafter, this bottle was going to last me roughly 6 mos+ for how often I was going to give it. (The 50 ml was selling for $150 and the 100ml for $197 so I got the bigger bottle, made sense I thought)
Well, the bottle expiration date is 1/25/15. Thatās only 3.5 mos from now. Iām losing 6 doses if I stop using it on the expiration date. Is this a typical shelf life? Did I make a big mistake in assuming Iād have at least 6 mos. shelf life?
What can or should I do? Will it be ok to give after expiration date? Anyone have advice?
[QUOTE=wishnwell;7796513]
I got my Pentosan in today for the first time, shipped from Wedgewood. I havenāt started my horse on it yet because I have questions first. I have the usual bottle of 250 mg/ml formulation in a 100 ml bottle. When I did my math, after loading dose and 2x month injections thereafter, this bottle was going to last me roughly 6 mos+ for how often I was going to give it. (The 50 ml was selling for $150 and the 100ml for $197 so I got the bigger bottle, made sense I thought)
Well, the bottle expiration date is 1/25/15. Thatās only 3.5 mos from now. Iām losing 6 doses if I stop using it on the expiration date. Is this a typical shelf life? Did I make a big mistake in assuming Iād have at least 6 mos. shelf life?
What can or should I do? Will it be ok to give after expiration date? Anyone have advice?[/QUOTE]
I would call Wedgewood and see what they say. Iām not a doctor or vet, but I think that, generally, meds can still be effective after the expiration date, but will begin to lose their potency as time goes on. I would be interested to hear what Wedgewood tells you; will you please update us?
[QUOTE=wishnwell;7788789]
So just when I think my prayers were answered, Iām confused again. For the last year Iāve done a TON of reading on Pentosan vs Adequan. I really am leaning toward Pentosan because of the feedback of others and the cost factor. My vet would not give a script for it though and then Adequan was not available. UGhH!
So I have a new Vet and YES! They will prescribe me Pentosanā¦but they told me there is no loading dose, just give 5ccās a week, every week. I have never heard this method beforeā¦plus my horse is about 1200lbs. I thought for sure Iād give 6ccās. Has anyone given a horse of that size just 5ccās and it work? My horse is an OTTB with 64 races in his past and about 14 yrs old now. What do you think? Everyone I see on here is giving the 6ccās. I also canāt imagine giving it weekly, my thoughts were- loading dose of 6ccās weekly, for 4 wks. Then 6ccās every 2-4 wks thereafter.[/QUOTE]
I have not heard of the dosage that your vet has recommended. Perhaps you can ask them to explain? My horse is also around 1200 lbs and I put him on the loading dose of 6cc once a week for 4 weeks, and now give him 6 ccs once every 3-3.5 weeks. (I started at once every 4 weeks, but it seemed that he would be a little stiff at the very end of that time, so I started giving a few days earlier.) I did pretty extensive research before starting Pentosan, and everything supported this dosage timing.
[QUOTE=wishnwell;7796513]
Well, the bottle expiration date is 1/25/15. Thatās only 3.5 mos from now. Iām losing 6 doses if I stop using it on the expiration date. [/QUOTE] This summer my vet told me that the shelf life had been extended on the Pentosan he orders fromā¦shoot, not at the barn right now, but it has Wyck in the name. Anway, before this they had a very short expiration date and he had told me to keep it in the refrigerator and as long as it did not turn dark brown, it was still useable after the expiration date. I do not know how accurate this is, but I always refrigerate it and it has never turned dark brown so I keep using it. Maybe it never does, hahaha.
Currently Wedgewood wonāt work with me. Since my vet called it in, they will only speak to her regarding this matter. So I left her a messageā¦
As I told them, the math on dosages prescribed + the size of the bottle + average shelf life of 6 mos, I would have been fine with the bottle. Frustrating
Well I just have to say I LOVE MY VET! Sheās the bomb! Sheās calling Wedgewood and getting me some sort of credit for the unusable portions of the bottle.
[QUOTE=wishnwell;7798211]
Well I just have to say I LOVE MY VET! Sheās the bomb! Sheās calling Wedgewood and getting me some sort of credit for the unusable portions of the bottle.[/QUOTE]
Perfect!!
After reading this tread and talking to my vet, I started my āall over body soreā 8 yr old Paint gelding on Pentosan - and I have been more than pleased with the results! The combination of getting his feet in good condition with an excellent farrier and the Pentosan - but heās a changed horse for the better! He no longer pins his ears while grooming, heās adjusting better than ever, heās so much more forward in his movement and itās just obvious that he is overall feeling a heck of a lot better. I am very pleased! Iām not sure which compounding pharmacy she getās her supply from, but it costs me $145 for the 50ml bottle an does not need to be refrigerated as it was with my first bottle. I loaded him for a month with 6ccās and Iām just about to give him another shot now as itās been a month since his last injection. I also started my retired 17 yr old gelding on it and he is doing great too - heās got navicluar and hock issues and heās become big man on campus again! I rode him for the first time in a year and he had no lameness issues (he had become pretty gimpy on his front right) that I could detect at just a walk and jog - and he was a lot happier too! Iām sold. Itās cost effective and the results speak for themselves in my book!
Has anyone tried giving it once a week for longer than the loading dose?
[QUOTE=runNjump86;8066210]
Has anyone tried giving it once a week for longer than the loading dose?[/QUOTE]
Yes, I have. It seemed to help, certainly more than the monthly or bi-weekly schedules I had tried. However, in my case, he continued to decline due to non-joint-related issues and is now on Previcox with monthly Pentosan. So, I am not a good example.
I realize Iām bringing this thread back from the dead but wanted to chime in a little.
I recently bought an OTTB who was being given a shot of Legend every 4-6 months, which my Vet (High Performance Vet with an affinity for Lameness related Sports Medicine) thought was absolutely pointless. We decided to try Pentosan and she recommended one shot every 30 - 60 days as needed. She didnāt feel the loading dose was necessary, and had supporting evidence showing that it didnāt serve much purpose aside from perhaps getting the āfull effectsā a little sooner. Sheās had 1 injection so far, and I purchased 3 in total. She advised that I should notice some improvement within a week post injection, and full effects following the second dose. My mare showed mild changes in her hocks but is considered sound (flexed a 0 on 3/4 legs, and a 1 - 2 on the 4th) so we are just doing it for maintenance sake.
I paid, I believe, $60 per 6mL vile, and I am in Canada.
Itās now available in the US from KineticVet, via FarmVet and other companies. Now that the AFL showed enormous improvements in 50 of their professional (human) playersāincluding one whoād had to retire from playing due to massive osteoarthritisāall of a sudden, the US decided it was just fine to use it here after all. Paradigm Pharmaceuticals did a human trial with these players, positive news of which came out in March, and published results in June. Voila! In July, Pentosan is now available here. So glad. Took long enough.
I get it compounded from Wedgewood with a vet script. 30 mL bottle for $97. I give 6mL at a time.
This is very interestingā¦so maybe not necessary to do the one shot every four weeks??
Per some previous but older posts, Iāve used it after it expired by a few months and it was fine. Youāre also better off getting the 50ml bottle from Wedgewood for $119 or $109, canāt remember- but that gives you 8 doses so a better deal than 30ml bottle.
