Have done both…have 2 JRTs (half sisters) who both have some allergies.
Both have been on cytopoint for a few years (frequency depends…fall/spring seem to be worse for the itching). Mine did get this odd growth on her paw that can happen with the cytopoint. My mom’s dog didn’t seem to have a good response to cytopoint the last time.
This fall they were both being super itchy again…my mom decided to try the Apoquel on her dog. It has made a very significant difference. I was going to try that with my dog…but the vet said the growth on the paw would be more likely to happen again with the apoquel so we went and stuck with cytopoint. It has helped…we were also doing either claritin or zyrtec before the cytopoint.
I also listened to a horse allergy webinar not long ago and they commented that if you don’t see a good response with apoquel in the first 2 weeks, then it probably won’t work for that animal. They were talking about horses, but guessing it’s similar with the dogs. My mare is on allergy shots and I will say that they have helped her a lot! My dog is older, so starting the shots now just didn’t really make sense…my mare is young, so hoping that the shots will get her symptoms to be more manageable.