I saw a few older topics on this without much in the way of feedback so wanted to see if anyone has used any of the supplements using Quinaquanone with any success? It was recommended to me by someone who coincidentally also sells the product, and the US website is pretty sketchy. Some additional googling came up with a few other supplements now offering the ingredient for a more interesting price point and some preliminary understanding of what the hell it even is- a more bioavailable form of vitamin K that can better translate to the desired outcome. Looks like Hygain makes a pretty cheap supplement with it. Any collective COTH wisdom?
So according to Hygain, Quinaquanone is a " a water soluble and bioavailable form of Vitamin K1 and K2"
What is your horse’s diet?
According to the NRC, a “Vitamin K deficiency in horses due to inadequate vitamin K consumption has not been identified” (p117)
So, probably not something I’d spend money on
New horse, so haven’t pinned down the diet specifically yet, (probably will end up staying on tribute wholesome blends balancer around 1-2 lb a day) but at least for the winter there isn’t going to be any fresh grass and from what I see, vitamin K degrades quickly in hay: Vitamin K: Essential for Bone Development in Horses - Kentucky Equine Research (ker.com) I can’t find any of the studies they reference, but it seems like there’s a proposed mechanism at least. The Bone Kare is 100 a month which isn’t something I would spend money on when for the same price I could do a couple rounds of adequan a year, but if my math is right the hygain version is around $15 per month which is a price point I’d be willing to give a shot to something that doesn’t have good specific peer reviewed data.
My comprehensive VMS has Vitamin K. Do we know that it is not already in most supplements?
It is in supplements but allegedly not as well absorbed in that format: LINK - CH 8 has some interesting info. I wish I could find the skinner study that paper references as showing this form is better absorbed, but no luck.
I know the balancer he is on does not include any vitamin K, nor does the other concentrate that he might end up on. He’s a bit of a chub and the breeder described his prior diet as a little hay if he is in the stall, and a handful of beet pulp if he is inside when the others are eating so it’s a little bit of trial and error to see what we can feed him without blowing him up like a tick.
that’s because no deficiency has ever been found outside of extenuating circumstances. I can’t say I’ve ever seen it in any GA of any feed/balancer I’ve looked at.
Your link requires a login 
This study says
The soluble form of the vitamin, KQ was the most efficiently absorbed.
But it also says
While supplementation of vitamin K using Quinaquanone (KQ) did not affect vitamin K1
plasma concentrations in mares, this implies that circulating plasma concentrations of vitamin
K may not be a reliable indicator of overall vitamin K status. Osteocalcin has been implicated
as a more reliable indicator of overall vitamin K status.
So maybe those studies looking at actual K aren’t looking at the better marker
In paying closer attention, it seems Quinaquanone is to regular K, as Emcelle/Nano-E/Elevate WS are to regular Vit E - they micellized or otherwise made vitamin K water-soluble to bypass the first stages of digestion, so it is better- and faster-absorbed.
But what matters more is what it does to the plasma
