Sure, but these seem like reasonable questions to want multiple perspectives on. And sometimes these kinds of trials are used before there’s a specific “something you are hoping to find” (e.g. to distinguish between pain and behavioral issues), and can you blame someone for reaching out to the community when they’re in NQR/undiagnosed issue purgatory?
OP, I’m not sure I’d count on an NSAID trial to definitively rule in/out saddle fit, GI, or repro, but I’ve never used a banamine/dex combo for such a trial. I wouldn’t expect NSAIDs to have much ulcer-relief effect even in the short term, necessarily – on the contrary, I’ve seen symptomatic ulcer flares develop quickly from just a couple doses of banamine. But if you’re continuing omeprazole at a treatment+ dose the risk of that should be pretty low.
It’s hard to say a lot more about what issues can be indicated by a NSAID trial, as that’s a very open ended question. IME they’re best for determining whether a problem is ultimately pain-related vs. arising from some other cause. The kinds of pain sources it can reveal depend on the symptoms or performance issues involved, typically. I’ve seen it be helpful in confirming physical pain that ended up arising from hard-to-diagnose body parts (e.g. neck arthritis, kissing spine). But I’m not sure if the dex (steroid) component of your protocol is there for its general anti-inflammatory properties (e.g. to help arthritis) or to target some other inflammatory response. That’s really where your vet’s specific reasoning would be more helpful than community bute trial experience.
I hope you get to the bottom of whatever is going on with your horse!
