I fully believe there’s something we don’t understand about feline nutrition that leads to a lot of them dying of kidney failure Some of it is certainly that dry food isn’t really suitable for them, but I suspect it’s more complicated than just that.
@Sherry99 there is not enough joint stuff in the food to make a difference. 1/2c of dry food is in the 50g range. That gives you 20 mg of glucosamine and 15 mg of chrondroitin if your little girl is eating 1/2c of food a day (the feeding guidelines say 1/4 to 1/2 c per day for a cat that weighs 5-9 lbs; she may be only eating 1/4c.) Cosequin contains 125 mg glucosamine and 100 mg of chondroitin, with directions to dose once to twice daily. Huge difference!
Have you found the cerenia useful for her vomiting? I’ve never seen much improvements in my cats using just cerenia, but do like it quite a lot when paired with zofran. Cerenia has some neat visceral pain relief qualities, too. (But if I’m picking one antinausea med, it’s zofran, no question!)
I have a kitty on mirtazipine right now (along with pepcid) and I’m just so pleased with her improvement. She’s eating better but she’s also just happier. It might be worth a trial with your kitty to see what changes. There’s no reason to hold off on some of these meds until end of life