Posting to share my story in case anyone runs into something similar. My 5 (?) year old Boxer has some instability in her knees. I have done lots of knee repairs on previous Boxers and am holding off on her for now for lots of reasons. At any rate, during her recent annual exam, I suggested we get her started on canine adequan. Vet administered the adequan and completed her annual physical. That was at 5PM. By 4AM the next morning poor pup got up and vomited her entire dinner on the carpet. Proceeded to be nauseous throughout the morning with some grass eating and vomiting. I went to work for a few hours hoping if she was allowed to rest quietly in the house the issue would resolve. Came home at lunch to more vomit so I called in and got her right to the vet. Doctor attributes the nausea to a reaction to adequan. Gave her some Cerenia, dex, sub q fluids and famotidine. Dog was groggy the entire night, ate a small meal and kept it down. The next morning kept down her breakfast and was back to normal 24 hours later.
I generally think of adequan as a fairly benign supportive measure. Not any more! This dog will not see an adequan injection again, that’s for sure. Has anyone else had similar responses in their dogs? The literature does say that nausea can be a side effect but I sure didn’t think it was going to happen to us after using it uneventfully on lots of other dogs.
Im not risking it though LOL
we got home and he vomited, the vomiting continued until 8 a.m. the next morning. I gave him a dosage of cerenia that I have on hand, and made him some organic chicken and rice, boiled. I called the vet and reported the symptoms because it was not just vomit it was projectile vomit. they agreed with the cerenia and the mild diet, and said to hold off on the next dose of adequan. they called to do a follow-up on Saturday afternoon, and I said he had eaten a little bit but not had any water. Finally at 6 p.m. he had water. Two hours later he was having massive bouts of diarrhea. thankfully I have cerenia and metronidazole on hand, so I just gave him that. if this doesn’t clear up by tomorrow morning, I will take him to the emergency vet. Every dog is different, every pet is different, But I will never give this drug to my sweet puppy again. To note, aside from the vomiting, the biggest thing that I noticed was his mood was depressed. I have searched other sites, and found that depressed mood is something that other pet owners have noticed as well.