OP, we first tested 4 1/2 years ago. I purchased my horse knowing he was stopping at Training level fences cross country. I wondered if there was a health issue, but he had a normal vetting, despite my mentioning my concerns to the vet. On my first ride after getting him home, my friend rode behind me. She commented that his tail was very crooked. I worried more, and we sent the EPM test to Pathogenes, which is the vet’s usual lab for EPM tests. He was very positive. Most vets that I have talked with don’t do a repeat test. Since his signs were so subtle, we did repeat testing. After 3 days of Orogin, my horse’s tail was almost normal. His titer stayed high, so we kept treating. Finally, after ?10 days of Orogin, ?2 weeks of Neuroquel, and ? A month of Protazil, his titer started dropping. We tested every 3 month for 3 years. The titer went up once during that time, which prompted another few weeks of Neuroquel. It finally went to negative about a year ago. His tail continues to be normal and he never stops at a jump on those occasions when I let a friend jump him.
EPM is hard to figure out. I feel fortunate that we figured out a treatment plan that worked for my horse. .