Failed selective reduction of twin pregnancy

Hi all,

I had a recent upsetting finding for my pregnant mare and am unable to consult with my local vets until next week, so am a a bit of a loss about what to think and wanted to reach out to more experienced breeders to see if any of you had any knowledge around this.

I posted about my mare here last last summer, but as a brief update, after consult with my vets and staff at Spy Coast (the stallion owner) we decided to see if she would take before they stopped collections for the year. She ended up becoming pregnant on the first try and I (stupidly) thought, great! She’s read the book on this pregnancy thing!

We did the early twin check and only one embryonic vesicle was found. At the 30 - 45 day heart beat check however, we found a second heart beat. My vets conferred with specialists and we decided to plan on a selective reduction at the specialist clinic at 120 days (if she didn’t bail us out and naturally reduce the pregnancy). When that time came, I shipped her to the clinic, but we were unable to do the procedure because of the location of the fetus the vets had identified for reduction. So I shipped her home and brought her back about three weeks later.

The second trip they were able to do the procedure (they did a transcutaneous, ultrasound guided reduction, injecting procaine penicillin in the heart of the fetus identified for reduction). The following day my mare was rechecked and the discharge paper said the fetus identified for reduction no longer had a heartbeat while the other one did. Success! Now I had to administer regumate for two weeks and then re-check with ultrasound.

Yesterday was the follow-up ultrasound. I was confident my mare had not expelled both fetuses, but of course there was the risk the other one had died too and she was carrying two dead fetuses. My vet here found the heart beat for the twin we had wanted to keep right away, so success again! She went to see if she could visualize the other one and…. Found another heartbeat. I was able to speak with the specialist who did the procedure today and he advised that although they had not seen a heartbeat at the check the day after the clinic, the penicillin with which they had injected the fetus likely impeded the ability to visualize the heart.

So now I have a mare at about 150 days gestation, with twins. :frowning: one is smaller, and the heartbeat was on the lowest end of the normal range, per my vet. The specialist vet said that I could try to reduce the pregnancy again, or terminate the whole pregnancy.

My vet was out of the office today, so I haven’t been able to discuss the best steps with her, but I’m very torn. I’m hoping that the measurements my vet took yesterday will shine some light on how the fetus we wanted to keep is developing, to help guide me a little more. What would you do, CotHers? Is the risk of placental insufficiency already significant enough that i wouldn’t be saving a viable foal? I don’t want to put my mare through a still birth or neonatal death. I’d be willing to try the procedure again, but it would be the third 8+ hour trip out to state to the specialist, which makes me hesitant.

That’s a terrible spot to be in, for you and your mare both. I’m very sorry.

Personally, in your shoes, I would probably choose to terminate the pregnancy at this point. As hard as it would be, it seems like you and your vets have tried every other option with no success.

((hugs))

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Thank you for your thoughts (and sympathy, it’s been like a soap opera with all the twists and turns). That was what I was thinking the best course of action would be, but was struggling to shift my mindset from trying to preserve the pregnancy to recognizing this one isn’t a success.

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What a horrible predicament, I am so sorry. I would have to discuss it in more detail with my vets but my initial thought is to go down swinging. The worst case is you lose both foals anyway right? Best of luck no matter what you choose.

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Thank you so much for your thoughts! I do want to see what my local vets think about viability, I’ve been anxiety digging into the research so I can go into it with the best background possible. I appreciate everyone here who took the time to comment, I want to do the right thing by my mare and this pregnancy

I know nothing about breeding and am sorry you are in this position. I’m w Laurierace- I’d go down swinging. Good for you for doing research…what about calling big TB breeding farms and seeing if anyone can offer advice?

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I agree with this (though admit I have no breeding experience). As long as it is safe for the mare, trying to keep one foal viable seems like the right next step.

Jingles for your mare and you!

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Is there a point where termination of one or both becomes untenable or impossible? A hard stop, where you have to make a choice, and if you don’t, the only option is proceeding with the pregnancy, and just crossing your fingers?

I’d be wondering if that smaller “lowest end of normal” heart rate fetus is really on its way to being unviable and if waiting just a little longer resolves this question. If there’s a window to act that’s closing, maybe you just don’t have time to wait and see, but if that’s not the case, can you wait and see? Rescan in a few weeks?

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That’s a good question! The specialist who did the procedure the first time said that 180 days is the cut off, so I have a little over a month.

I’m hoping to make a plan this Monday, when my local vets are back in the office! I think sooner is usually better, because as the pregnancy progresses there is more of a risk of neither fetus getting sufficient nutrients.

The poster who asked about reaching out to thoroughbred farms - that’s a great idea too! I’ve been digging into the research but speaking to someone who has personal experience would be very valuable. I know the thoroughbred farms must have to make decisions like this sometimes, because one of the techs when I dropped my mare off mentioned that they can do the procedure onsite for the local thoroughbreds.

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I would think with one fetus considerably larger, that you are in a better position should you be unable to terminate the other. The larger one may remain viable and the smaller one may or may not survive. I would want some answers about the risk to the mare of proceeding vs terminating the entire pregnancy.

A happy story to give you some hope: Friend bred her WB mare and mare had a seemingly normal pregnancy. Shortly before she was due, friend saw mare in paddock with a foal! Upon closer look, there was a second, smaller foal hiding behind mama. Both foals survived with one being considerably larger. Since it was a G year, the bigger foal was named Gemini and the smaller was GA Bonus. The little filly remained pony-sized last I knew of her.

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TBs mares that are carrying twins have one pinched at 15 or 30 days (as you attempted to do). If there was a case where a TB broodmare reached 150 days with 2 viable embryos, I can almost guarantee that the decision would be made to terminate the pregnancy. First because of the risk of continuing the pregnancy to a $$$$$ mare, and second because in this scenario it’s doubtful that even if there is one surviving foal, it would have the robust constitution needed to compete in a demanding career.

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That’s a great story! What a good outcome, and what cute names!

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The impact of potential placental insufficiency at this stage had worried me too about the foal’s ultimate development - definitely something I’ll be talking to my vets about tomorrow when we make a plan!

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@OneBellBoot, best of luck with the outcome, whichever way you choose to go!

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If you want some truly expert input into this (not that you haven’t gotten valuable facts already), this FB group is great, run by Jos Mottershead of Equine Reproduction
https://www.facebook.com/groups/144573995719975

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Oh wonderful, thank you for this! Both my vets at home are out of the office today, so I’ve just been worrying about my girl, I’d love as much info as I can get

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An update for those interested: we tried the transcutaneous ultrasound guided reduction again today and it looks, so far, successful! The vet was able to visualize the heart during the administration of the procaine penicillin and observe the heart stopping. At the time of the procedure, the fetus we are trying to save still had a heart beat. So fingers crossed that tomorrow’s check shows the same news!

Thank you to everyone who commented for your ideas and support!

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Jingling that everything was successful!!!

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Fingers crossed for you!

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jingles that the next check is the news you want :chains:

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