Greater Boston I think you’d need to be a millionaire to buy a 5 unit in Boston.
I’m not sure that anyone could find even a shack for the figures you mentioned even in Greater Boston – so it is probably all relative to the area. A single family home on a postage stamp starts at $300k here, and that’s a fixer-upper and/or demo.
While I think I paid an absolute fortune (and thinking about it is just eyewatering, as the queen of frugality), we paid about $200k less than market value and could, today, sell this for twice what we bought it for last June.
It is definitely easier where the math is more favorable. SO and I have semi-dependent family members here, so we’re tied to the area for the foreseeable future, but my goal is to move out of the house we own in 5 years. Both of us have jobs that cannot be remote, either, so that is a consideration when deciding QOL/living costs with wages as well.