I was researching treatment for laminitis and found a study that showed interesting results for chronic laminitis by treating with tramadol and a subanesthetic dose of ketamine to reduce arterial blood pressure.
It’s a small study but seems promising … I wonder if anyone has heard of this treatment/know anyone who has tried anything like it?
What would have been a reason to not have a 3rd group of ketamine-only? That would have made the study much more interesting.
But regardless, it’s still interesting!
Interesting. Tramados by itself is not very effective given orally in horses (https://www.ncbi.nlm.nih.gov/pubmed/18177320), so it’s not something I’ve given much thought to.
Was there any further study after this? This seems to be have been done in 2012.
Well, only 15 horses. Hard to really say anything. My first question is whether they all have “chronic laminitis” for the same reason. What exactly is “chronic laminitis” anyway? (e.g. laminitis for no known cause? Or metabolic horses not being treated for their metabolic issue?)
In the end it probably doesn’t matter (much) why, as the end cause is the same - inflammation of the lamina. 15 horses isn’t a lot, but it sure it interesting still
I can’t find much else that suggests that this been researched/tested, but I have seen a few vet studies/conferences that point away from stacking NSAIDs, for example, and using ketamine and xylizine for more effective pain management. I was curious about pain management as I heard recently about a very sad experience where the pain from laminitis could not be managed, and I don’t think the vets were thinking outside of the box.
I thought this had some useful information to keep in mind.
https://www.vetfolio.com/learn/article/acute-pain-management-in-the-horse
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