So there was no fever involved? Do you at all think that your horse had been suffering from anaplasmosis all along? My horse has been sensitive to touch alternating with wanting to be groomed hard, particularly on hindquarters.
No fever, just weird hypersensitivity to touch that was worse on the left side. She may have had anaplasmosis all along but she was positive to Pathogenes blood test for epm and did respond to the epm meds. She was never neurological and rode fine, but just wasnāt her normal friendly self. Sheās loved at my farm since she was 6 months old and is now 10yrs old, so I know her and fortunately my vet doesnāt discount my concerns.
Iāve also had to treat her for ulcers despite the fact that she lives outside with constant forage.
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So I tried him on Nano-E when I was treating him with Rebalance and he wouldnāt eat it on top of his grain, which is critical to the success of the barn employees remembering to give it - has to go in food. Iāve had this problem with my boy before where he just doesnāt like liquid additives to his food (including oil). Heāll toss the bucket around so violently that he dumps everything out. I tried a ground feeder pan and he REALLY dumps everything out with those. No such issues as long as what Iām putting in his feed isnāt liquid 
So now heās on a pelleted vitamin E supplement that I think is lipid soluble but he will eat it with his feed and the guys are good about remembering to toss the premeasured amount in his grain since itās all set up for them.
This is great! My vet and I decided to try Protazil since heāll happily eat the pellets but was becoming aggrieved about oral medication after 6 weeks of ReBalance. Heās still weak in that leg and Iām trying to stay hopeful. He was very unbalanced on that leg when he had to be sedated for a recent dental float - couldnāt even flip his toe so his hoof would lie flat on the ground and I had to help steady him by gently pulling on his tail. None of his other three feet had that problem so it was like the sedation kind of unmasked the symptoms for a bit.
I use the human capsules available on Amazon. Lipid soluble is fat soluble, which is not water soluble. You need water soluble for neurological benefits.
All vitamin E is fat-soluble as a vitamin. Itās a bit confusing LOL
Nano-E, Emcelle, and Elevate W.S. (water-soluble) have been nano-dispersed (first) and micellized (last 2) so that they skip the conversion process in the body and therefore have higher bioavailability
Everything else is ānormalā vitamin E. But all that matters is whether what youāre giving is keeping his blood level where itās supposed to be
Not exactly 
Any form that gets and keeps a normal blood level is good. There are EPM horses who only need a regular Vit E to keep a healthy level. There are some non-EPM horses who are so low they need a water-soluble version, and usually, but not always, can then transition to a regular version after the w-s version gets their level to normal
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