I have a mare who is very reactive to her vaccines and has always been. And gets a pretty severe localized reaction-- very acute swelling and soreness at the injection site that lasts for well over a week.
She has gets hives in the summer from allergies and nearly every vet I’ve had has remarked that horses with reactive skin are often extra sensitive/reactive to shots as well.
She’s always a tense mess when getting her shots, which of course does not help, as often the vet is unable to give the shots with the ease and precision that would help minimize some of the reaction. Often by the time she’s getting her last shot, the horse is 4 feet off the ground.
The last couple years I’ve been giving her banimine prior to injections and have been giving her some exercise right after shots. This helped quite a bit in the beginning and her swelling with banimine has been less than it was with bute. But the last couple times the reactions have been pretty severe again.
Spreading out the vaccines over multiple weeks doesn’t help much because then she is just sore and swollen for an overall longer time. And she gets harder to give the injections to.
Curious to hear from others who’ve had horses with reactions to see if there were particular things that seemed to help?
The vet has suggested that dex could help. I’m a bit weary of giving steroids in general, and like to avoid it if possible. But if it’s true that a small dosage the morning off/day before could make a distinct difference, then I’m willing to try it. Though I also wonder about giving an immune suppressant at the time of vaccines and whether that might create other types of long or short term problems.