My vet mentioned that there is a newer version of the injectable omeprazole that supposedly has had less reactions. Has anyone tried this yet?
I have a 23 year old 1/2 arab mare I am fostering for a rescue. I’ve had her since the middle of November 2024. She came to me very thin and with a lot of anxiety. Had her teeth done a few days later, lots of points and ulcers along both sides of the jaw. Anyway, I hoped that would resolve some of her issues, but it really hasn’t, so last week I had the vet out to do a complete exam, and he suggested Omeprazole injectable for ulcers along with Zycosan for osteoarthritis.Haven’t really seen any changes yet, but the meds have only been on board a few days. She is also on Firocoxib.I’m curious if other people have tried the injectable omeprazole.
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I don’t know about a new version but we did experiment (through our vet) with injectable omeprazole and it caused a big painful lump at injection site. It was a great idea in theory but not workable for us.
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I have! It’s the one from Epicur, the same formula from the clinical trials (which supposedly had <1% reactions). We’re on dose 3/4 and haven’t had any swelling or other side effects.
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can i ask the protocol for it (how often/how long do you have to give it, is there a taper/rebound, etc) and how much it cost (not that it matters, just want to make sure i’m over it if i’m going to be shocked lol)?
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I used it on my guy in the fall - note that I am in Canada and I have heard that the kind we use here is not the same as the version in the US, but that may have changed. The Canadian one was supposed to have less side effects. We decided to try it because my horse lived out and gastroguard wasn’t really an option. He had minor squamous and moderate glandular ulcers, so he was on sucralfate and misoprostol. The vet thought the injectable omeprazole would be effective enough in combination with the other products. It was approx $300 an injection (cdn) and they are done 5-7 days apart - I believe 5 days has been found to be the most effective. We only did two. He did have a bit of a reaction to the first, a bit of a bump on the neck that took about a week to finally go down and general swelling and stiffness. The second one was fine. He’s never had any reaction to any injection or medication before.
If I were just treating with omeprazole I would stick with GG if possible. GG also provides a second round for free if you rescope and the ulcers haven’t healed, which is benefit you lose out on with the injections.
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I gave the injections last Saturday evening. No swelling yet. Although I’ve read there may be more of a reaction with the second dose.
Per my vet 2 dosages 7 days apart, and then we’ll see how she’s doing. Here it was $210.00 per dose.
Just checked my receipt, it was 952+tax (238/dose). The standard protocol is 4 doses, 5-7 days apart, but product literature says 5 days is better for glandular ulcers. No tapering that I’ve seen.
My horse has primarily pyloric ulcers and the omeprazole is playing more of a supporting role alongside a 8 week misoprostol regimen, so I am doing 7 day intervals just to stretch it out slightly more over the treatment length.
With the miso I won’t be able to tell if the injectable omeprazole works on its own, but it definitely makes everyone’s lives 10000% easier. Now I don’t have to be there at 6am every day to do gastrogard early enough for an empty stomach and at least 30 min before miso, which would have been a huge pain.
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please keep me posted on reactions and results!
Will do. Just gave the second dose tonight.
