Is this as good as people say it is for horses?Testimonials are pretty great but all companies have testimonials. I’m pretty intrigued by it and tempted to try it but 81$ for a month seems like a lot to just try it out. it does go down to 40$ then after that.
Can you explain how you understand this to work?
When I Google I find a mix of legitimate science papers that describe very narrow investigations, and then a bunch of sales pitch inflated claims that don’t seem very credible. Can you explain what you are getting for $81 and what you expect it to do, and why you take the claims seriously?
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They have a Facebook page look up nrf2 equine, and ppl are recommending it on Facebook groups. Idk how it works. It’s really only made for humans I guess but ppl are giving it there horses and dogs for least a few years. It’s a pill. 81$ is just for the first month bc they say u need to give two pills a day for a month then one pill a day there on out.
Everything I’ve seen from the people pushing it is pseudoscientific babble.
And there are potential hazards—this is not a bandwagon I’d jump on without more extensive documentation of efficacy and safety. (Though I suspect the stuff being peddled isn’t the real deal, any road.)
“Nuclear factor erythroid 2–related factor 2 (NRF2) is a key regulator of the cellular antioxidant response. Phenolic antioxidants have long been known to protect against chemical carcinogens, typically by activating the NRF2 pathway. Numerous clinical trials of NRF2 activators are under way for treatment of disorders ranging from cancer to schizophrenia. One NRF2 activator, dimethyl fumarate, is approved for treatment of multiple sclerosis. Prolonged activation of NRF2, however, causes tissue damage: In clinical trials for type 2 diabetes, NRF2 activators initially showed promise for renal protection, but studies of longer duration were discontinued early due to increased mortality, hypertension, and albuminuria. There may be a role for NRF2 inhibitors in clinical medicine.”
From Science-Translational Medicine. Dec 2017. Bolding mine.
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Beware of strange threads started by first time posters.
“Granite it does go down to 40$ then after that.” LOL
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If you don’t know how it works and the explanation on line doesn’t make sense, then don’t use it. All legitimate forms of medicine have physical explanations. When you run up against something with no real explanation you are in the realm of faith healing, mlm scams, and other foolishness. Run.
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When I googled I also found that the term was being used in connection with an herbal wonderpill that was also outed as an mlm scam.
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Umm I was simply asking if ppl use this. It’s a thing and it’s all over nutrition Facebook group.
I totally understand your skepticism, I recognize this poster who is using yet another handle, so while the name is new, the poster isn’t.
B - if it sounds too good to be true, it probably is.
This product is nothing but a few herbs put together into a tiny pill. Bacoba, ashwaganda, green tea powder, turmeric, and I forget what the other 1-2 things are. They are basic antioxidants and adaptogens.
None of the ingredients are magic, they all have some valid research behind them. But by the same token, the claims the company makes are not at all backed up by valid research, no matter what its proponents and distributors tell you. There are zero - zero - studies showing any replication of any of the effects allegedly shown by other studies. There are studies which show things didn’t happen, in the face of studies which claim to show that did happen. Most studies on the product are on rats/mice, or in vitro. No studies in horses (shocker).
I know you are always looking for the next magic bullet for something. If you want to try it, go for it - it’s not likely to hurt. anything but your wallet. And if you do try it, be very, very clinically objective about what issues you are looking to resolve, and be very diligent about documenting every single thing that goes on in your horse’s life while on it.
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All I see is a bunch of breathless testimonials, along with exhortations to avoid buying from anyone but the person pimping it on that page.
Kinda short on actual scientific proof.
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LOL some local “horsemen” are marketing it. “Horsemen” are in quotation marks for a reason. I figured there must be turmeric in it, no surprise there. This is the first time I’ve seen any info on what is actually in it. Horse owners are so gullible and susceptible to marketing schemes in their desperation to find a magic pill to cure all ills, it’s amazing. Hey, I’m sure using a pill is a better plan that actually learning some horsemanship skills or consulting a veterinarian.
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As of 2017, this herbal supplement was being distributed as a multi level marketing scheme (a model that is inherently fraudulent) and received a warning letter from the US FDA on false medical claims.
https://sciencebasedmedicine.org/protandim-update-new-studies-and-an-fda-warning-letter/
There is also evidence the herbal formula can be actively harmful, not just useless.
As of 2017, this herbal supplement was being distributed as a multi level marketing scheme (a model that is inherently fraudulent) and received a warning letter from the US FDA on false medical claims.
https://sciencebasedmedicine.org/protandim-update-new-studies-and-an-fda-warning-letter/
There is also evidence the herbal formula can be actively harmful, not just useless.
Here is the link to possible dangers of the herbal formula.
https://sciencebasedmedicine.org/i-was-wrong-about-protandim/
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I posted a link to information from 2017 that said the FDA issued a warning letter about false medical.claims to the multi level marketing entity pushing this supplement. The link in my post made it unapproved so I imagine it will appear in the next 24 hours.
OP, the thing about most FB “nutrtion pages” is that they are very commonly multi level marketing schemes, and full of complete lies.
The multi level marketing scheme itself is fraudulent because nobody actually sells much of whatever their overpriced supplement or cosmetic is. Rather, the ultimate goal is to get the customers to become distributors and buy the pricey starter kit and then hook more distrbutors “down line” all of who accrue profits up the chain.
Every mlm marketer is desperate to recoup their own initial investment and will do and say anything to get more suckers involved in the chain.
Nothing said in this context of economic desperation can be trusted. If you want a good read, look up the true life stories of people who escaped from mlm schemes.
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:lol:
I Googled Nrf2 and found that it is a protein in the body. I have no idea what the OP is talking about paying $81 for.but the fact that they posted “81$” instead of “$81” makes me think whoever it is is not in the US so who knows what foreign products they are talking about?
I Googled Nrf2 and learned that it is a protein in the body, so what the OP is talking about paying $81 for is beyond me. I don’t think OP is in the US, since they posted 81$ and not $81, so who knows what product they mean?
I did post an LOL at your catching “granite,” but COTH is up to its “unapproved” antics again. 
LOL good catch!
Nrf2 is a protein in the body. I don’t think OP is in the US – giveaway is the “81$” instead of “$81”.
I wish this d*** COTH would quit unapproving my posts!
Yes. These “supplements” appear to be putative activators of the protein in question.
Yes, when I googled there was some serious medical research investigating aspects of this protein, and then there was the herbal supplements that claimed to activate it and cure every disease under the sun.
So either OP or the OPs sources are conflating the herbal pill and the actual protein in the body.
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