Regumate

Hello Everyone and Happy Thursday.
I have a mare who has been on regumate for 6 months. It seems to be working wonders. I have two questions, does anyone take there mares off regumate during less work time aka winter and do you gradually take off by reducing the CC’s? And 2nd ?? Does anyone do less CC then recommended. I know its suppose to be 1 CC for every 100lbs. Has anyone does around 8/7 CC’s?
Thanks in Advance

I took my mare off Regumate gradually over several days, before she went to pasture vacation, where she promptly went into full scale super skank heat for several days. I am going to bring her back in a month and re-evaluate if we need it over the winter. I didn’t get any vet advice on gradually reducing, but figured any medication should be reduced gradually. I am not entirely sure if I started to see behavior changes at 300 or 400 ccs.

As far as dosage, I was playing with minimal dosages and was keeping her 1150 lb super skanky self medicated fine on about 7 cc a day. I didn’t get the message about ccs per lb; certainly I never did 11 or 12 ccs!

I will keep riding daily in the winter once she comes back from pasture, so if she is getting cranky, she is going back on Regumate.

I feel there is little risk in experimenting with the lowest effective dose of Regumate. If the mare goes into heat or starts biting my foot when I’m riding, I can increase the dose. If this was human birth control obviously there’d be a risk of getting pregnant. But since I’m only using this to manage her moods, I think finding out the lowest effective dose is a good idea.

I believe the recommended dosage is 1 cc per 110 lbs. It takes about 3 days after you start administering to take effect. The mare will generally go into “heat” four days after discontinuing Regu-mate. The information from Merck doesn’t indicate that a dose tapering is needed when discontinuing the drug. With my mare, I have just stopped giving it in the winter, or when she won’t be ridden for a while. Never had a problem doing it this way.

https://www.merck-animal-health-usa…ate-Solution/1

On my mare there was total personality change for the better in 24 hours after starting it. I tapered her dosage off and put her out to pasture on a Friday and she was in full heat on Saturday.

I give my nearly 1300lbs mare 10cc as that’s what was recommended as the starting point by my vet. She is obviously very uncomfortable off the Regumate, and this dose works, so I don’t mess with it. My plan is to take her off it over the middle of winter when we don’t travel for clinics or shows and most mares in my area don’t cycle. For us, that will be at the end of October. She will go back on it at the beginning of March as that is when she started cycling last year. I wasn’t planning on tapering as that wasn’t recommended to me by either my vet nor is it in the manufacturer’s instructions for use.

Yeah probably the tapering was unnecessary. In the absence of any instruction it seemed like a good idea.

Curious though when all of you put your mare on Regumate did you ever get any diagnostics done to see if anything specific was bothering her like ovarian cysts, etc? I didn’t just put her on Regumate as a trial and it worked. But I’m wondering if I should also be having her checked for repro issues?

When I took my girl off of it, I just discontinued use. There are warnings against underdosing, so if you’ve been administering the minimum recommended amount for your mare’s weight, I wouldn’t give her any less.

My mare’s cycled twice since I took her off of it. The first one wasn’t very bad, this second cycle she seems back to her normal ways. In retrospect, I probably should have waited until October.