[QUOTE=Donella;6911572]
I suppose there is that chance that the caslix could make all the difference as that was never done previously but she looks decent conformationally?? .[/QUOTE]
Yes, it made a difference for me with 9 foals.
[QUOTE=AFOBGYN;6913622]
Have you thought of doing an embryo transplant? She seems like the perfect candidate.[/QUOTE]
That is what I think. A few years ago I had a St. Premium Hanoverian mare who was older and had had a few foals. I took her when her last foal was a yearling. She got in foal easily, and lost the pregnancy every time, once as far along as seven months. Unfortunately I don’t know what her biopsy score was, but to me, my mare and the OP’s are great candidates for ET.
Yes, I have strongly considered an ET but after reading this thread I am really leaning towards the DMSO lavage (if my repro vet will do it) and then breeding and caslixing ect and crossing fingers like crazy. If it doesn’t work this year then I would probably say she is unable to carry a foal and would go to an ET. I guess I just feel I should give it one more try, just in case a few small management changes end up doing the trick?
I just want to point out that there are two totally different things being talked about on this thread. Several people have mentioned success with a DMSO lavage for mares that have been difficult to get pregnant, and have referenced a possible biofilm problem. It is documented that a biofilm does result in some mares not being able to conceive, and DMSO is one of many treatments for that condition. However, this does not sound like the case for the OPs mare. This mare is conceiving and then losing the pregnancy, which means that a biofilm issue is not in play here. This is a classic case of probable pregnancy loss due to fibrosis in the uterus which is supported by the biopsy results in this case. A DMSO lavage may still be helpful, but for reducing fibrosis the DMSO concentration MAY need to be greater than that reported to be successful for the treatment of a biofilm. I say MAY because we are talking about an area where there is very little research and the treatment protocols are all over the map. Just want to make sure that we are comparing apples to apples here.
. A DMSO lavage may still be helpful, but for reducing fibrosis the DMSO concentration MAY need to be greater than that reported to be successful for the treatment of a biofilm. I say MAY because we are talking about an area where there is very little research and the treatment protocols are all over the map. Just want to make sure that we are comparing apples to apples here.
Thank you for clarifying, I wasn’t making the distinction so good to know! So what kind of concentration would you suggest for my girl if I were to do it?
I personally could not put myself or my mare through losing another foal and have chosen to do ETs only with her. I hope you are successful in whatever you choose to do.
I have thought of this too. It’s one thing for it to happen at 45 days and obviously quite another at 10 months. I WILL feel very guilty if that does happen, obviously. In all honesty I can probably only afford to try an ET with one mare this year and I have two other mares that I adore, that I bred, that are being aimed at performance careers and I know I won’t give them the time off to have a foal so ET will be the only option for them. If this were the only mare I needed to do an ET with I think I would just go that route this year and even scrap trying to have her carry. Gosh, I really just don’t know…
I don’t know very much about this, being a very small breeder, however my older mare did not get in foal the first year that I tried to breed her. Her biopsy score that year was a IIB. We rested her a year and re bred with fresh cooled, using oxy afterwards. She has since delivered 3 healthy foals and is pregnant with her 4th. I tried her with frozen semen and she would not conceive that way even though all appeared well when we did it. Based on that experience, I would hesitate to try frozen, just one more thing that could complicate things even if there is no concrete reason why. Good luck!
Bluemoon, I am so sorry to hear about your foal. That is just so heartbreaking…ughh. You are absolutely right, the highest highs and the lowest lows. Thank you for your well wishes though, I appreciate it. Crossing my fingers for you this season too, hopefully we both have Dante Weltino’s in 2013!
