Senior horse with Neurologic signs - EPM

My 24 year old heart horse shows mild neuro signs and I am pretty upset.

We’ve had a lot of rain lately so there was no much turnout into his big favorite pasture this spring. A couple weeks ago, when I finally let him into his big pasture he was pretty happy – galloping, chasing his buddy, bucking, rearing, romping and acting like a five year old. Which was unusual. Same day, he got out of his grazing muzzle which I found in a clover patch. When he came to the barn, he was walking slowly, not limping just kind of strangely and not cantering which he normally does because he wants dinner. I thought it was a tummy ache, called the vet because he didn’t finish dinner and he was given 1/2 dose of banamine. OK in the morning.

Next evening, when I walked him in the barn aisle, he was NQR – not limping or anything, just NQR. I don’t know what prompted me but I circled him and he didn’t cross his front feet at either direction. Vet came a few days later and she sees very mild neuro signs and says she’s never seen him like this before.

Bloodwork comes back negative on Lyme and on EPM from KY lab, he’s on the cusp titer-wise and they suggest re-testing in 2 - 4 weeks. Vet wants to do IRAP on his hocks.

He picks his fronts up too high and when backed up he circles his right hind. Pivots – does not circle on his right. To the left is iffy. No back pain. No fever. Eating ok. He spooks in the pasture now when he never did before. Starting a year ago, I have suspected he doesn’t see as well from one eye but vet has checked that and feels he’s ok.

I did loading dose of Equate Vit E – 20,000 and now giving 10,000. I have Transfer Factor Stress Formula ordered. Right now, we are giving him bute twice a day for 5 - 7 days to see if that makes a difference.

Over the years, have treated 2 other horses successfully with Marquis. And had to put down a young neuro horse who was determined by autopsy to have had a tumor. So I know the roller coaster ride.

The difference here is that this is a senior horse and I’m a senior, too. I don’t want to put my buddy through anything horrible. I also don’t want to let him waste away when he could be cured of whatever is going on. I love riding him! What can I say? He’s my everything! I would love to get a test done through Pathogenes but cannot find any vet in our area (Northern Virginia) who will do that. I don’t know if the Oroquin-10 is recommended for a senior horse. I also don’t want to risk losing my vet. I don’t know what to do – I abhor indecisiveness – and am just awfully upset.

I will value any input at all.
Thank you.

I háve not real input, just hope he gets straightened out.
I would have to rely on my vet’s opinion, and if that was too vague, or indecisive,
I would seek a 2nd opinion.
Best of luck with your boy!!

Thank you, TrailRides4Fun.

I so sorry. I have no wisdom for you but a lot of love and empathy. Very best wished for you both

Thank you, allons-y. I really appreciate that.

This sounds not good, but still hopeful. He can still graze and get around, it is possible that this is his aged body letting him know that all that running around was a bad idea, at least we can hope that. Jingles that he is comfortable and happy and this passes uneventfully as “one of those things”.

Thank you, ReSomething. Maybe it is just “one of those things.” Wouldn’t that be nice.

Where are you located? Here in the Northeast we often see some pretty funky symptoms from Lyme and Ehrlichia.

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We are in Northern Virginia and just did the Pathogenes blood test and 10 days of Oroquin. We will do the follow up blood in 6 weeks. The Oroquin was easy to use, as my horse ate it eagerly when I put the tablets in his feed. The blood test and Oroquin are not expensive, and I think are becoming accepted as an alternative diagnostic and treatment strategy.

When my EPM old man (he is 29 this year) shows symptoms of recurrence, we give him IV banamine , DMSO and dex (I think on that one) to reduce inflammation. Then we start him on the cocktail for a week.
This has happened now 4 times in the past 6 years.

Thanks so much dotneko!

I have heard that Dr Javier Donatelli in Poolesville is doing amazing work with EPM. The medication he uses is cheap enough and safe enough that a lot of people in the area just go ahead and treat with it when EPM is suspected. Someone I know who has seen several horses treated by him says the response is amazing.

http://equimed.com/location/16090

Thanks, Stacie. Do you know if Dr. Donatelli sells the medicine at his practice? Or if he works with the people at Orogin in Florida?

Can someone please tell me what pathogens test and Oroquin, Marquis and Transfer factor stress formula are???

I would get a second opinion with a different vet …and send blood to Pathogenes asap …was a cbc/Chem done? What about all the other tick borne infections such as Anaplasmosis, Erhlichia etc …what about a metabolic panel?? I wouldn’t be too scared about the borderline EPM bloodwork-most horses have been exposed …My young horse responded best to Orogin /Neuroquel from Pathogenes

also neck problems-arthritis/injury/stenosis can also mimic Epm and other neuro problems …I’d get a second opinion and possibly do neck Xrays to rule out…not that expensive and can inject if there’s arthitis

Don’t overlook the possibility of cervical arthritis appearing. Symptoms can absolutely mimic EPM. (Would need x-rays to diagnose - not that expensive, and then you could consider joint injections which are surprisingly inexpensive as well.)

I hope your horse improves soon. The uncertainty is really hard. You just want to know what you’re dealing with so you can make it better.
My senior TB (22 yrs) has experienced something similar, it started about right before Christmas 2015. We did two different EPM Tests from two different labs (one at onset, one at relapse two months later) both were negative as well as Lyme titer. My vet thinks most likely it’s cervical injury or arthritis. The first treatment was Dex, then prednisolone and daily Vitamin E. He improved, but had a relapse again in February. We re-did the Dex/prednisolone treatment, acupuncture and he’s now on one tab Previcox daily, 1 prednisolone, 4,000 IU Natural Vitamin E and homeopathic herbs for hind end weakness prescribed by my vet. He actually looks good now, no leaning or crab walking, but he’s not 100%. He’s still weak when picking up his feet and I doubt he’ll be ridden again, but as long as he’s still with me, I can deal with that.