I’m dealing with this too right now. Mine was blocked toe to stifle first to rule out any contributing issues. We did inject the SI without further diagnostics (my choice) and that did help immensely…for a few months. Then I was right back to square one, and in fact it was getting worse.
We did also do a repeat block of the hind suspensory (his symptoms did mimic that issue somewhat) but that was not the problem. We x-rayed the stifle too just to be sure (clean as a whistle) then off he went for a bone scan.
Mine turned out to be soft tissue as slp2 mentioned, not bone involvement, so that explains why the injection cleared up the soreness temporarily but as we continued to work, he continued to get worse.
The university that did his bone scan did not ultrasound - they told me it wasn’t able to penetrate far enough down, although slp2’s back-specialty vet did diagnose hers. Therefore, mine can’t be 100% confirmed, although they said they were very confident that’s the issue based on his presentation of symptoms and the thorough workups he’d already had done.
We’re coming near the end of our 3 months stall rest (hand walking allowed, and turn out into a tiny pen for a couple hours a day so he can only stand, roll, and walk ). Fingers are crossed we can begin the under saddle rehab next week after our vet re-check!
Oh, and the university believes mine had an old more minor SI injury from the track (his left SI sits lower than the right always), and he does have a bit of lower-joint hock arthritis. They think he’s gotten himself into a cycle of inflammation and compensation between the hocks and back, so although we had been treating both issues, perhaps our timing wasn’t good (we had done hocks but not SI, then did SI but not hocks, etc) and he finally couldn’t cope any longer.