I have a mare I think this will be great for…have any of you used this product before? If so…tell me about your experiences. TIA!
My repro specialist uses it on all my frozen semen mares. We have very good success, but I couldn’t tell you how much difference it is making as we don’t breed them without it.
My vet adminsters settle when breeding my mares on their foal heat.
Any others?
This mare pools and I have to use antibiotics and oxy to get her in foal. I was hoping the “Settle” would eliminate the oxy as she can get colicy with the oxy.
[QUOTE=paintjumper;5359692]
This mare pools and I have to use antibiotics and oxy to get her in foal. I was hoping the “Settle” would eliminate the oxy as she can get colicy with the oxy.[/QUOTE]
Settle does not do the same thing as oxytocin. Settle is used for a lot of off-label situations, but it has only been studied in and labeled for treating mares that have endometritis due to strep zooepidemicus. If you are using the appropriate dose of oxytocin (it is a very small dose) then the mare should certainly not be colicky.
we use the smallest dose…
she is just very sensitive to it. Breakes out in a sweat, pawing, laying down to roll…the whole colic scene for about 30-40 minutes. Everytime. I may try it anyway.
[QUOTE=paintjumper;5360174]
she is just very sensitive to it. Breakes out in a sweat, pawing, laying down to roll…the whole colic scene for about 30-40 minutes. Everytime. I may try it anyway.[/QUOTE]
What dose are you using? Those are highly unusual signs if you are giving the micro-dose that is used for breeding.
I would also have to wonder if it is possible that Cloprostenol (“Estrumate”) or another prostaglandin are being given rather than oxytocin…
The vet draws it up for me…???
I called her when the symptoms started the first time and she said it was the smallest dose and that she had never had that type of reaction before. I have not bred her for 4 years because I don’t have the heart to watch what she does. Without the oxy…no foal… ever.
I think the Settle would be easier on her…I may try it “just for the heck of it”.
I’m confused. Settle doesn’t work for clearance issues so if your mare has clearance issues, this isn’t going to help. I have never heard of a mare that reacts to oxy this way. How utterly strange!
I also have never heard of a mare reacting in such a way to oxytocin. I suspect you are giving something else and wonder why. I’d definitely recheck with your vet to clarify matters.
[QUOTE=Equine Reproduction;5360239]
I would also have to wonder if it is possible that Cloprostenol (“Estrumate”) or another prostaglandin are being given rather than oxytocin…[/QUOTE]
This would make more sense.
I’ll check with her…
I do remember we gave it in several doses hours apart but I don’t remember the interval. This is the only mare that has done this, the other mare with the same protocol never even looked up from her grazing. My mare…it was horrible, this poor mare handled labor FAR better. I did this 3 years…got a foal every time, with out it, no foal ever. I have not tried anymore because I did not have the heart. I know the Settle is not for pooling but I had hoped that it might work for an off label use. I think I will give it a try anyway…if I get a baby it will have been worth the try. If no baby…nothing will have changed. I was just hoping someone had tried it before me. My husband says I am always braving new ground…I’ll let you guys know if it works. I will be using fresh semen so that will make things a little easier…maybe 
Settle will NOT do the same as oxytocin. I’m not saying it won’t help your mare, but if fluid is an issue then it isn’t going to help get rid of that. Oxytocin causes contractions in the uterus that literally push the fluid out of the cervix. Settle is an immuno-stimulant that helps to fight certain infections and inflammation in the uterus. It will do nothing to move fluid out of the uterus. Two completely different classes of drugs. It won’t hurt to try it, but I just want to make it clear that we are talking about two completely different modes of action here.
I am aware of the differences
What I am HOPING is the Settle will decrease, through it’s action, the amount of fluid. I am also going to put her on Immunal in a CHANCE it will help with the same thing. We’ll see, if it works…I will let you know. I am going to wait till Spring is in the air…no early stuff since I am already behind the eight ball with her. Wish us luck…we can certainly use it.
Ponygirl…
I am HOPING the Settle will make “clearance” not an issue. I am hoping the Settle will keep the fluid to a minimum. We’ll see.
How did the Immunal work for you paintjumper? I have just ordered mine for a 14 y/o mare who has had issues catching.
Sorry, I forgot about this thread…
She’s IN FOAL!!! I gave her the Immunal daily for 2 months and I gave the Settle IU every day of heat until we bred her. She caught on the first heat…I can’t say for sure if it was the Immunal or the Settle or both, but it worked for us THIS time. If it works again next year, I will be sold. I have NEVER gotten her in foal without the oxy, never until now.
I have another mare I am doing this with that became infected after retaining a placenta, we’ll see if her cytology improves. I’ll report back…if I remember, sorry.
A big, huge congrats paintjumper!
