[QUOTE=jherold;7542338]
I was trying to avoid doubling up on the Flea protection if possible. I would like to keep the amount of chemicals I give this dog limited if possible. She acts weird and runs around the house for several hours after FrontLine. So it must bother her in some fashion.
Thanks for your suggestions. Keep them coming![/QUOTE]
In case you missed this list:
Many different drugs and drug classes have been reported to cause problems in Collies and other herding breed dogs that carry the MDR1 mutation.
You might send your question into the contact & see if they have any suggestions, also given that your dog is showing reactivity
We are currently seeking samples from dogs of the herding breeds (Collies, Australian Shepherds, etc.) that have experienced unexpected reactions to drugs when administered at normal doses.
(not sure how current this is)
I’d be cautious with Ivermectin even at the “safe” dose as your collie has already shown reactivity,
From the BC Board
The reason I say this is because my dog who had seizures, which I think I could connect to my use of ivermectin (all based on a seizure diary where I also kept track of flea, tick, and HW preventive applications), has not had any seizures that I know of since last May. I took her off ivermectin the preceding October, once the correlation suggested itself. When my vet suggested using Interceptor for Phoebe, I questioned the fact that it is also in the same chemical class as the drugs that cause problems in sensitive dogs, and whether it made sense to try it if ivermectin could be triggering her seizures. He said that milbemycin oxime does not cross the blood/brain barrier as efficiently as ivermectin does. She’s been on Interceptor for a year now and has had no seizures that I have witnessed. So if the trigger for her seizures was indeed ivermectin, then it seems that another drug from the same class of chemicals is not a trigger
Poster also included a quote from the AWCA - again there are research groups listed that you might contact.
There are some interesting posts (eg read the last entry on this page) regarding the safety of Ivermection at Heartguard doses.
“Safety” of toxins is always debatable, basically, dosages are chosen that are shown effective against the target organism, while host organism reactivity is below a certain threshold - it is naive to assume that the host is not experiencing ANY toxic effects.
Knowing your tick species may help in choosing an effective control program.
Re your GSD, you may be able to teach her to protect & herd “her” chickens but that’s much easier if you have suitable trainers to work with 