Last Friday my vet gave my 12yr old Dutch Wb mare the flu/rhino vaccine , sedated for teeth floating and Banamine as she had laminitis a few years prior and we pre treat her ever since. The following evening when I brought her inside she was very dull and lethargic, laid down just a few minutes after being brought in and didn’t want to eat her dinner …she had a low grade fever of 101.3 so vet advised to give another dose of banamine and we chalked it up as a mild vaccine reaction…she perked up a bit and eventually ate her dinner …the next morning (Sunday) she again didn’t want to eat but very slowly finished her breakfast, got turned out for the day and seemed ok but was still very dull …vet advised to give Banamine again that evening …fast forward to Monday morning she was still lethargic /dull and no interest in her meals and had not eaten much hay …also only 1 poop overnight…had vet out (Monday ) she now had a impaction …vet tubed with Magna lax , epsom salt and electrolytes…gave another dose Banamine …she only had 1 more poop that day …vet back out again Tuesday as she’s still the same -lethargic /dull/ no appetite and only pooping 1-2 times in 24 hrs -repeated rectal -still had hard dry poop , tubed again with same stuff and gave dose of Banamine and gave 5 liters IV fluids with dextrose …she remained the same …fast forward now to Wednesday…vet out again …repeated rectal , large amount hard dry poop , tubes again , and took blood for cbc & chemistry…got results that showed elevated creatinine of 4.3 ( high end of normal is 1.8-2) elevated BUN and …potassium also slightly elevated …i then brought her immediately to New Bolten Center -they admitted her to the hospital…took more blood-her creatinine was now 5.9 and blood also detected in urinalysis …they put her on 24 hrs IV fluids …she started to perk back up and pass manure and appetite slowly returned…next day Thursday creatinine down to 4.3…she remained bright & comfortable …Friday creatinine down to 4…I requested ultrasound of the kidneys which showed that they were enlarged-everything else unremarkable…I also requested to test for leptospirosis-still waiting on those results …Saturday down to 3.5…Sunday 3.1, Monday 2.8 and today 2.6 despite being on continuous iv fluids …New Bolten seems to think this is possibly from the banamine even though she was given appropriate amounts (12cc’s once / day for 5 days) beings that banamine is a nephrotoxic drug …my regular vet and myself don’t feel it’s from that and there’s got to be an underlying cause ?? Things that are on my list of possibilities are the vaccine because that’s the only thing that she had and was fine prior to it …other things I’ve been racking my brain with of what could it be from the supplements she takes for her Pssm2 and MFM?? She’s been on KER MFM pellets since last November when she got diagnosed-that supplement is an ultra concentrated Amino Acid /Protein supplement ??
I asked NBC if it’s concerning that her levels still aren’t back to normal after 6 days on IV fluids …they said they don’t love that it’s taking this long but sometimes it does …they aren’t overly concerned and seem optimistic that she will be ok…however everything I’ve read on this says generally you will see a 30-50% decrease in creatinine level after 24hrs on iv fluids ….my regular vet on the other hand is quite doom and gloom about this saying she could potentially need to be euthanized if her levels go back up once off fluids …and also about her long term prognosis in the future saying it’s unlikely to think that she won’t ever need bute or banamine the rest of her life …what if she colics , gets injured etc etc then what do you do ? He put the fear of god in my telling me that her kidneys are damaged and you can’t reverse it …and they will onlY worsen over time.
Anyhow …has anyone ever dealt with something like this ?? Please tell me there’s hope of her to return to normalcy