That has been my thought too. I’d rather have a vigorous fan a-fanning flies away than constant insecticide spritzing.
I realize that pyrethrins are considered to be less noxious than some other insecticides because they are derived from chrysanthemums.
But here’s some stuff from the EPA:
Toxic Effects
The critical toxicological effects of pyrethrins are (1) neurobehavioral effects (tremors, labored breathing, hyperactivity, secretory signs, matted coats), following acute, short-term, and chronic exposure, with nervous system lesions observed in the rat and mouse following acute exposure; (2) thyroid effects, following chronic exposure in the rat and dog; and (3) liver effects, following short- and long-term exposure in the rat, dog, and mouse.
Following inhalation exposure, neurobehavioral effects were observed initially, and respiratory tract lesions were observed at all dose levels. The neurobehavioral effects and the mode of action on the sodium channel are considered relevant to humans because the effects are observed in both the rat and mouse, and the mode of action affects a basic function of the nervous system that is common to all animals.
Lots more here:
http://www.epa.gov/pesticides/reregistration/REDs/pyrethrins_red.pdf