For all owners of herding breeds...know about MDR1!

Washington State is in the for front in the research for the MDR1 gene, found in herding breeds…please read on their website. This gene is found in herding breeds…50% of Aussie’s and 70% in collies, ect. The gene does not effect life for those that carry the gene, unless they get the wrong drug. They have a list on their website. Many vets are not up on this… My vet told me today that that a client of hers went to the emergency vet over the holiday and they killed the collie with the wrong drugs…This is a high end clinic with all the bells and whistles . My Aussie has one gene from one parent and a normal gene from the other. She has been in Chemo for almost a year, at Davis. It is a careful balance of drugs to save her and does not kill her… Ivermectin and Imodium could kill her…Talk to you vet about this.

Thanks for this information ~

It’s easy to do the DNA test to see if your dog is affected or not.
http://www.animalgenetics.us/Canine/Genetic_Disease/MDR1.asp

[QUOTE=Nadia;8736071]
Many vets are not up on this… [/QUOTE]

Thanks for the insult. It actually is common knowledge among veterinarians.

[QUOTE=Marshfield;8736471]
Thanks for the insult. It actually is common knowledge among veterinarians.[/QUOTE]

I thought so.

It has been common knowledge in dog circles for decades.

I was wondering if there was something new/different to this?

No insult intended, sorry if I offended you…but when I heard that even one dog died at a emergency clinic ,That should have know better, it was worth my time to put this out there.

I hope people already know this, but I guess it can’t hurt to have a reminder.

I ALWAYS treat ALL herding breed or mixed breed dogs as though they will react to Invermectin unless I have specific evidence to the contrary.

Is it really all herding breeds as I’ve never heard it linked to Bouviers…

[QUOTE=Where’sMyWhite;8736613]
Is it really all herding breeds as I’ve never heard it linked to Bouviers…[/QUOTE]

http://vcpl.vetmed.wsu.edu/affected-breeds

Not all breeds, but any mixes should be considered affected unless you know they are not.

I don’t have any herding breeds but I did not know Immodium would be a problem. I knew about Ivermectin, of course, and think most dog people have heard about this concern. But I just gave my dog Immodium at my vet’s recommendation - and of course he knows the breed - but I didn’t realize that for some breeds it would be dangerous.

I’ll share this information with my friends, just in case!

[QUOTE=Marshfield;8736471]
Thanks for the insult. It actually is common knowledge among veterinarians.[/QUOTE]

This.

[QUOTE=Marshfield;8736471]
Thanks for the insult. It actually is common knowledge among veterinarians.[/QUOTE]

yup…cool…pretty sure that’s like day 1 in vet school. “White feet, don’t treat with ivermectin”

Also shame on your vet for insinuating another vet killed the collie with the wrong drugs. That could be the case or your vet could be mistaken. Really shows your vets true color as a person and lack of ethics. And people wonder why vets are committing suicide left and right.

Acepromazine is also one of the problem drugs. Here is a current list…

www.vcpl.vetmed.wsu.edu/problem-drugs

I apologized once, already…I am not bashing all vets, just passing on information some dog owners may not know…just trying to be informative

Now it’s my turn to insult back. Sometimes it’s not that one vet insinuates another vet did something wrong, because we do our absolute best not to throw each other under the bus, but it is often that the owner didn’t listen carefully enough.

And yeah, we knew about this before the general public. Thanks.

I worry when vets get “offended” by something like the OP’s post. Vets should be glad that OP is reminding people.
OP, no need to apologize. I worry about vets who have time to post on boards. My vets are working and keeping up on the latest discoveries, not posting on boards on line.
If you aren’t busy with paying clients, then go volunteer with rescues, you vets who have so much time to post online!:mad:

[QUOTE=invinoveritas;8738206]
If you aren’t busy with paying clients, then go volunteer with rescues, you vets who have so much time to post online!:mad:[/QUOTE]

:eek: Vets aren’t allowed to have downtime to do whatever they might feel like doing???

Frankly, I appreciate that there are vets on this board who are willing to take the time to add in their comments and/or advice.

I’m in the group that is a little disappointed in how the vets are reacting to the OP’s post.
I’ve had dogs my whole life, but they’ve always been retrievers or pointers. I recently acquired a young female who is half Aussie. I knew about Ivermectin, but I didn’t know about Ace and immodium. As an owner I’d rather be informed so shame on you for trying to insult the OP or keep her quiet.

Not all vets are created equal, the same as doctors, nurses, dentists, etc. Just because this is obvious to you, doesn’t mean that a new vet, or one trained somewhere else is immune from slipping up…

How I choose to spend my free time is none of your d*mn business.

I don’t mind someone telling people about this, but to flat out say many vets don’t know about it is, indeed, insulting. One can educate without saying vets are not in the know of something so bloody common.

[QUOTE=invinoveritas;8738206]
I worry when vets get “offended” by something like the OP’s post. Vets should be glad that OP is reminding people.
OP, no need to apologize. I worry about vets who have time to post on boards. My vets are working and keeping up on the latest discoveries, not posting on boards on line.
If you aren’t busy with paying clients, then go volunteer with rescues, you vets who have so much time to post online!:mad:[/QUOTE]

Wow, that was totally unnecessary. You’re lucky that some of us decide to speak up and offer free advice from time to time. We ARE volunteering in a way, by doing that. Not all of us have time to go to rescues or wherever and give away our services. It’s much easier to sit at home on our days off, lunch breaks, wherever, and browse the internet. And hey, if we decide to chip in and give you a bit of free advice, then super. I’ve passed by threads I could’ve commented on MANY times because I was too busy.

When I’m at work, I’m at work and not cruising the boards. When I’m off, I go on COTH. It’s MY TIME to go online.

And FWIW, spreading knowledge, even common, isn’t a bad thing. It’s when you insinuate that all the vets don’t know something that is insulting. If I had a client come in and speak down to me about something I knew about, then I’d be offended in a little way, even if I wasn’t going to show it. I don’t know what happened with the OP and it sounds like it wasn’t a first hand account anyway, so let’s just leave it at that.

MDR1, it’s a mutation, it does exist. There ya go.

(and ivermectin is NOT an emergency drug IMHO, so why was an ER doc giving it anyway? Half the time I treat ivermectin overdoses in horse owners who are dumb enough to give their dogs their horse’s paste dewormer…MDR1 mutation or not!) Also I never prescribe immodium for anything! there is no need to if you’re treating diarrhea correctly…)

[QUOTE=DrBeckett;8738825]
I don’t mind someone telling people about this, but to flat out say many vets don’t know about it is, indeed, insulting. One can educate without saying vets are not in the know of something so bloody common.[/QUOTE]

I can’t find anywhere in this thread where anyone said that “many vets don’t know about this”. I really hope that you just got up on the wrong side of the bed, you really seem to be taking this PSA way too personally.

Again thank you OP, I didn’t know about the immodium which is something that we often have hanging around the house.