My 9 yo Ridgeback has a sesamoid fracture and my vet is excited about using pentosan on her. I’m not sure if he’d really been aware of it before I brought it up, but he’s really interested in using it after some research.
Has anyone here used pentosan on their dog? Results? Were you happy with it?
Since the answer seems to be no here…
We gave Koa her first injection on Tuesday. 0.4 cc sub q for a 75 lb dog. We will see how it goes!
Yes, our boxer has been on Pentosan injections for over 18 months now and seems to have been a common treatment for dogs over here (New Zealand) for quite some time. He has arthritis of the spine and knees and he has 4-5 weekly injections. It does definitely seem to help him, he is more free in his movement. It’s hard to tell if it helps him from a pain perspective these days as he is also on a daily Caprieve tablet as well as his Sasha’s Blend (been on that for a couple of years now, really happy with how that goes too).
I would love to try it on my Pom. Her dose would be so tiny I don’t think I could draw it up even if I used an insulin syringe.
[QUOTE=Laurierace;7252273]
I would love to try it on my Pom. Her dose would be so tiny I don’t think I could draw it up even if I used an insulin syringe.[/QUOTE]
You could get a compounding pharmacy to make you a bottle at a lower concentration.
My 11 year old dog has been on it for 2 years. I can tell a difference (he’s stiff) if I forget and give a dose late, and also it helps to slow down cartilage degradation so it can’t hurt!
I’ve seen it make a huge difference, noteably on a Border collie that was ancient, the owners were thinking of having her euthanized because she couldn’t walk her arthritis was so bad… She was soooooo much better on the pentosan! I’ve only seen a few dogs get such a good effect from it but wow! And they changed nothing else, no food/supplements or whatever added.
I’m using it on my shepherd to help prevent knee arthritis. (He’s had two TPLO’s). He’s 7yrs old, and almost a year since the 2nd surgery and so far, so good. He gets 0.5 cc of my horse’s prescription per my vet’s recommendation.
My dog is on Cartophan, which is the doggie formulation of Pentosan. She is a new dog. I was told to add Metecam if she needed it, but am reluctant to give her something that might upset her stomach on long term use.
Cartophan costs me $21.00 / month, so I consider it very reasonable to keep her happier.
After a week, I swear we’re seeing an improvement in Koa.
Need to get her in next week to continue. Those of you who are using it, how often do you give it?
Need to have a conversation with my vet about cost next, as it’s about $25 all in every injection. Looking at the dose, I can do it for a buck or less from Wedgewood. I appreciate him going out of his way to research and try this, though, so we’ll make sure he’s square before we switch over to a compounded product that I give…
Have you considered using Legend instead?
I just got a 4 Ml bottle, which would be 2 doses for a wolfhound. I haven’t tried it yet, as I am not comfortable giving IV injections, but my wolfhound’s brother and sister in another state have had it to great effect. Just waiting til I can get to my vet, we have discussed it and they are willing.
It is such an individual thing as to what they will respond to, I have used Legend, adequan, and pentosan in horses, and so far just Adequan in dogs, which has been very helpful the several times I have used it, I mean on several different dogs.
With the horses, I’ve seen the best response with Legend, but I have to get someone else to give it! I can find the vein just fine, but can’t make myself inject into it. IM, no problem!
I used to give IV injections in small animals all the time when I was 20…can’t do it now.
Pentosan has been around a loooooong time for dogs and cats and is marketed under Cartrophen. It seems work better on cats - minima to moderatel response with dogs. However, its cheaper than both polyglycan and adequan.
Dogs seem to respond better to polglycan and adequan when given IM. You can also use polglycan IA in dogs.
Pentosan or Cartrophen has been the GO TO drug for cats with arthritis for decades.
Squish, has your practice used Legend for dogs yet? (I know it is off label).
[QUOTE=Houndhill;7255347]
Squish, has your practice used Legend for dogs yet? (I know it is off label).[/QUOTE]
Not for IA. Not sure about IV, its possible if a client wanted it. Anecdotally, we have seen the best results with an IA injection of polyglycan followed up by a series of IM injections. However, we do what the client wishes…can only recommend what we feel works best. I think Legend would be more costly to the client as they cant do the IV injections at home. However, I could be wrong…it does occasionally happen lol.
Squishy - since you are on this thread -
The Cartrophan made a remarkable difference in our bull terrier. She is positively youthful again. But if we needed to ‘up’ her medications, what wold you recommend. I’m not sure of Metecam since I thought it was hard on their stomachs and liver? Shall I ask for Polyglycan? How about cost?
[QUOTE=Foxtrot’s;7263474]
Squishy - since you are on this thread -
The Cartrophan made a remarkable difference in our bull terrier. She is positively youthful again. But if we needed to ‘up’ her medications, what wold you recommend. I’m not sure of Metecam since I thought it was hard on their stomachs and liver? Shall I ask for Polyglycan? How about cost?[/QUOTE]
Does she have arthritis in one particular joint? We find the most useful treatment for elbow OA is IA injections, followed by IM. For this, our hospital uses polyglycan, however, I am not saying its better or worse than the other similar joint injections out there.
Depending on your hospital, you may find the Cartrophan cheaper than polyglycan or adequan…or vice versa. We use polyglycan much more than Cartrophan or Adequan so we can offer it to clients cheaper. Again, personal preference but what works for one may not work for another. These are not like NSAIDs, they do not reduce inflammation and do not work in the same way the NSAIDs do…so at some point those are something you may need to consider if the arthritis gets bad.
Any NSAID can have consequences like GI ulceration and organ damage. However, often times these are palliative treatments so we are willing to take these risks. For those younger dogs who need support longer term, lower dose NSAIDs generally are recommended and come with less side effects. And FWIW, even normal dosaging doesn’t cause issues in the majority of dogs, or it wouldn’t be offered. SOME dogs are sensitive to them, so its always something to keep an eye on.
I like metacam over previcox, dermax and rimadyl because dosing can be far more accurate and easy to half/quarter etc. You can dose it to the pound, whereas the others in pill form are rounded up/down. But, I have my dog on Previcox because for me its easier if she is staying with a friend, if I have to get someone else to pill her etc. its “easier” than wondering if someone else is going to mess up a metacam dosage.
But, there’s lots of things you can do before NSAID management. IA, or up the frequency of cartrophan, or give another brand a try. Fish oil added to the food, low impact exercise, addition of oral glucosamine suppliments like cosequin. Synthetic’s like tramadol are also relatively low with the side effects.
Thanks - very helpful, Squishy.
Now, may I ask the origin of your screen name? My imagination makes it seem a little odd for a veterinarian!
[QUOTE=Foxtrot’s;7264240]
Thanks - very helpful, Squishy.
Now, may I ask the origin of your screen name? My imagination makes it seem a little odd for a veterinarian![/QUOTE]
Not a vet…so don’t take my opinion as one. But, having worked in referral practice for fifteen years, I hear it over and over when discussing with clients and the boarded surgeons.
Bascially, I love bunnies and want to squish them all. To me, there is nothing more squishable than a wee bun hehe.
[QUOTE=SquishTheBunny;7264308]
Not a vet…so don’t take my opinion as one. But, having worked in referral practice for fifteen years, I hear it over and over when discussing with clients and the boarded surgeons.
Bascially, I love bunnies and want to squish them all. To me, there is nothing more squishable than a wee bun hehe.[/QUOTE]
Didn’t I recall a somewhat different explanation as to your name? Come on now, tell all!
For those using on their dogs what dosage are you giving?
And are you using the 250mg/mL?
I talked to my (dog) vet about it a while ago and can’t remember the mg/kg amount he told me.
bump ?
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