I noticed that bute-less has caught on lately as a ‘natural remedy to control inflammation’ and looked into it a little bit. The ingredients are:
Wheat Middings - flavoring
Alfalfa Meal - flavoring
Dried Molasses - flavoring
Yucca Schidigera Extract - No proven effect in horses on joint health
Mineral Oil - Not sure why this is in here honestly, probably as a binder
Devil’s Claw Root - contains harpagoside, which is an NSAID just like Bute
Natural and Artificial Flavors added - flavoring
Vitamin B-12 supplement - supplement that probably doesn’t do much for inflammation
So…what we’ve done here is taken a known substance like Bute or Previcox with a known metabolic pathway and dosage and well-understood side effect profile, taken it away because it might cause stomach ulcers, and replaced it with another substance that also has an effect on the same metabolic pathway that causes stomach ulcers, except now it’s at an unknown strength and dosage.
Does this seem really silly or even outright DANGEROUS to anyone else?
The vast majority of supplements seem to be like this. At best, they don’t do anything, and at worst, they can have severe detrimental effects on the animal (such as when you give them an unknown dose of a known NSAID such as devil’s claw continuously).
A few really do work, like hylauronic acid. A few work because they contain a pharmacological agent, like raspberry leaves, which are high in magnesium, or again, devil’s claw.
I just cannot wrap my head around why this stuff is all so popular.