Just started my 13 year old QH gelding on Pentosan today. 
He doesnāt have any really stiffness yet but occasionally walking out of his stall he is stiff and after laying down he is stiff. He was x-rayed when he was 7 and showed some hock arthritis.
Hopefully this will keep him going strong!
[QUOTE=JSwan;6348175]
Wow!!! Wonderful wonderful news!!!
Kent Allen treated by Irish horse and recommended Pentosan twice a month for him, instead of once a month. Just FYI as you start working her.
Iām really happy sheās doing better.[/QUOTE]
Full dose or half dose?
How is Sophie doing?
Full dose.
Matter of fact that horse is going back there for his annual exam. If you like Iāll pass along any juicy tidbits Kent has for my horse.
You donāt know my other horse - that little bugger is 20 years old. Heās been on Pentosan twice a month as well.
Had a jumping lesson on him this morning.
[QUOTE=Addison;6361226]
How is Sophie doing?[/QUOTE]
Itās been about 10 days since her last injection and sheās doing great. I decided to quit lunging her before I ride but Monday she was so eager to GO that I came close to rethinking that plan. I didnāt get to ride yesterday, spent the afternoon waiting for Fed Ex who usually comes between 11-1 and didnāt show up till after 5. It was a shipment of inverts for my reef tnk so something that had to e tended to on arrival.
Weāll see how she goes today. As soon as she starts slacking off Iāve warned her sheāll get another shot
[QUOTE=JSwan;6361296]
Full dose.
Matter of fact that horse is going back there for his annual exam. If you like Iāll pass along any juicy tidbits Kent has for my horse.
You donāt know my other horse - that little bugger is 20 years old. Heās been on Pentosan twice a month as well.
Had a jumping lesson on him this morning. :)[/QUOTE]
Thanks I would appreciate it
Iād like to give Pentosan a try, too.
A few years ago I gave my mare Adequan when she had a foot problem, and the results were amazing. She turned into a very decent mover! lol I am hoping it will be the same with Pentosan.
Sheās not lame, but she raced until I bought her when she was 4, and she is 13 now. She is on MSM, and thatās it. We donāt compete, except in hunter paces, and we do jump for fun about 3ā, so I think a little help would be nice for her.
Iām planning to do the 4 shots loading dose, and a floow-up after one month, then hopefully, only once every 6 months or so.
She is small, 15.1h and lightly built, so should I just give her 5 mL, or the ānormalā 6 mL?
Thatās great news about Sophieā¦i hope it continues!
[QUOTE=carolprudm;6361793]
Itās been about 10 days since her last injection and sheās doing great. I decided to quit lunging her before I ride but Monday she was so eager to GO that I came close to rethinking that plan. I didnāt get to ride yesterday, spent the afternoon waiting for Fed Ex who usually comes between 11-1 and didnāt show up till after 5. It was a shipment of inverts for my reef tnk so something that had to e tended to on arrival.
Weāll see how she goes today. As soon as she starts slacking off Iāve warned her sheāll get another shot[/QUOTE]
Carolprudm (or any of you), would you mind sharing what was wrong with your mare? I have a horse with an undiagnosable lameness and Iām thinking of trying Adequan or Pentosan as a last ditch effort.
BTW, I have a reef tank too! They are great.
[QUOTE=Addison;6362684]
Thatās great news about Sophieā¦i hope it continues![/QUOTE]
Me too. Weāve been struggling with issues since this past Oct. Had her saddle fitted, teeth done, she just didnāt want to work. FINALLY in Jan she started limping. Nerve blocks and xrays pointed to her fetlock, had that injected, went OK for 2 months. Then she just didnāt want to work again, not forward, hard to bridle. Finally she started limping again which led me to start her on Pentosan.
Now I know, if she doesnāt want to work itās time for a shot.
Itās funny, sheās turned out most of the time, in during the heat of the day but I rarely see her move faster than a walk when sheās out. But when I put a saddle on her and take her into the ring sheās all GO
After reading this thread and seeing so many success stories with pentosan, I wondered if it was used for arthritis in people. I googled it and found it is called Elmiron in human medicine and is apparently only used to treat bladder cystitis. It is related to heparin and the side effects were a little scary. Has anyone had any problem with bleeding as a side effect with their horse or any other side effect?
Library > Search Results
pentosan polysulfate sodium
Pronunciation: PEN toe san POL ee SUL fate SOE dee um
Brand: Elmiron
Elmiron 100mg
white, imprinted with BNP 7600
slide 1 of 1
What is the most important information I should know about pentosan polysulfate sodium?
Before taking pentosan polysulfate sodium, tell your doctor if you have a bleeding or blood clotting disorder, a history of aneurysm or stroke, a stomach ulcer, intestinal polyps, diverticulitis, or liver disease.
Take the medicine on an empty stomach, at least 1 hour before or 2 hours after a meal.
Call your doctor at once if you have any easy bruising or unusual bleeding such as nosebleed, blood in your urine or stools, rectal bleeding, coughing up blood, bleeding gums, or feeling like you might pass out.
To be sure this medication is helping your condition, your doctor will need to check your progress every 3 months. This will help your doctor determine how long to treat you with pentosan polysulfate sodium. You may also need blood tests to check for certain side effects. Visit your doctor regularly.
Tell your doctor if you use any other medications that can increase your risk of bleeding, including blood thinners, medications to treat or prevent blood clots, or an NSAID (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), indomethacin (Indocin), and others.
What is pentosan polysulfate sodium?
Pentosan polysulfate sodium works like an anticoagulant (blood thinner) that prevents the formation of blood clots. However, it is used to treat bladder pain and discomfort caused by cystitis (bladder inflammation or irritation).
Pentosan polysulfate sodium may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking pentosan polysulfate sodium?
You should not use this medication if you are allergic to pentosan polysulfate sodium.
To make sure you can safely take pentosan polysulfate sodium, tell your doctor if you have any of these other conditions:
a bleeding or blood clotting disorder;
a history of aneurysm or stroke;
a stomach ulcer, intestinal polyps or diverticulitis; or
liver disease.
FDA pregnancy category B. Pentosan polysulfate sodium is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether pentosan polysulfate sodium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take pentosan polysulfate sodium?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Take the medicine on an empty stomach, at least 1 hour before or 2 hours after a meal.
To be sure this medication is helping your condition, your doctor will need to check your progress every 3 months. This will help your doctor determine how long to treat you with pentosan polysulfate sodium. You may also need blood tests to check for certain side effects. Visit your doctor regularly.
If you need surgery, tell the surgeon ahead of time that you are using pentosan polysulfate sodium. You may need to stop using the medicine for a short time.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include easy bruising or unusual bleeding.
What should I avoid while taking pentosan polysulfate sodium?
Follow your doctorās instructions about any restrictions on food, beverages, or activity.
What are the possible side effects of pentosan polysulfate sodium?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
nosebleed;
blood in your urine or stools;
rectal bleeding;
coughing up blood;
bleeding gums; or
feeling like you might pass out.
Less serious side effects may include:
hair loss;
nausea, diarrhea, stomach pain;
headache;
mild dizziness;
depressed mood; or
mild itching or skin rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect pentosan polysulfate sodium?
Tell your doctor if you use any other medications that can increase your risk of bleeding, such as:
abciximab (ReoPro);
alteplase (Activase);
anagrelide (Agrylin);
argatroban (Acova);
aspirin;
bivalirudin (Angiomax);
cilostazol (Pletal);
clopidogrel (Plavix);
dalteparin (Fragmin);
dipyridamole (Persantine, Aggrenox);
enoxaparin (Lovenox);
eptifibatide (Integrelin);
fondaparinux (Arixtra);
heparin or warfarin (Coumadin);
lepirudin (Refludan);
prasugrel (Effient);
ticlopidine (Ticlid);
tirofiban (Aggrastat);
tenecteplase (TNKase);
urokinase (Abbokinase); or
an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.
This list is not complete and other drugs may interact with pentosan polysulfate sodium. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about pentosan polysulfate sodium.
Sophie got 6 ml 250 mg/ml so she is getting 1500 mg at most once a week. Sheās a big girl, just shy of 1400 lbs. I suspect the human dose would be at least once a day so over a period of weeks or months the human is getting a higher dose.
But to answer your question, no, I havenāt noticed any side effects
[QUOTE=happyfeet;6362706]
Carolprudm (or any of you), would you mind sharing what was wrong with your mare? I have a horse with an undiagnosable lameness and Iām thinking of trying Adequan or Pentosan as a last ditch effort.
BTW, I have a reef tank too! They are great.[/QUOTE]
She has changes in her fetlock joint, first pinpointed with nerve blocks then confirmed with digital x rays.
Here are some neat pics of daughters reef tank
https://picasaweb.google.com/carolp3231/20110801#
taken with my Kodak 980 in burst mode
Havenāt noticed any side effects at all.
However, you do not give the IM Pentosan injection within 24 hours of a joint injection - as it can increase the risk of bleeding.
Weāre not talking about gushes of blood. Weāre talking a pinprick.
RE:Elmiron
I googled this
The recommended starting dose for the treatment of interstitial cystitis is Elmiron 100 mg, three times a day. It is recommended that you take your Elmiron capsule with water, either one hour before or two hours after a meal.
http://bladder.emedtv.com/elmiron/elmiron-dosage.html
I just started my horses on Pentosan. While none of them are lame, they are getting on in years. I have four that are between the ages of 20-28. I am hoping it keeps them all comfortable and still able to go out for hacks.
Do people use it on younger guys that also donāt have any significant problems as a preventive? I also have two younger boys that are in full work and if I thought it would keep them comfy I certainly would use it in them.
One more thing. My vet just prescribed it for my 11 year old Cattledog and his dosage is 6 tablets once a week for 4 weeks. Hoping this makes a huge difference in him.
Carol, i would dearly love to try it for my arthritic knee. Seems like it would make all the difference, doesnāt it?
This is COMPLETELY anecdotal, but I gave two of mine a four shot series of Pentosan. Neither was lame or even off. One is an 11 year old that can be sticky on his lead changes. He is a lead changinā fool now. The other is a 15 year old that would come out stiff at trot. He starts off beautifully now. In fact, he feels so good, he has been quite fresh lately! May have to order some SmartCalm!
[QUOTE=lucky dog farm;6363527]
Carol, i would dearly love to try it for my arthritic knee. Seems like it would make all the difference, doesnāt it? :)[/QUOTE]
It is temptingā¦
JSWAN, please clear out your inbox
Itās been a little more than 2 and half weeks and Sophie is just a bit off. Iām giving her another shot and a loading dose of HA to try to stop it before it gets worse.
I think I will d/c the Smart packs, maybe go with Platinum Performance
Carol, Iām sorry I missed your message. Thereās room now. Please resend.
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