Xylazine (the horse drug) and its human abusers

WARNING! If you decide to read the article, there is a graphic picture of effects of drug on humans!

People do weird things with horse drugs. Now they’re mixing xylazine with fentanyl with dangerous effects. Thought I’d post this article just in case vets suddenly can’t get it.

https://www.nejm.org/doi/full/10.1056/NEJMp2303120

One of the scary things is that narcan doesn’t have any effect if someone is overdosing on xylazine.

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fentanyl deaths in 2021 were reported to be 70,601 as if that is not enough now the users adding more crap to whatever they are doing, if they are already using a deadly substance adding more stuff to it really should not be of much concern

honestly there is little to nothing that the average person can do to stop fools from killing themselves

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I am currently at work, a community crisis center. There is a 24 year old kid right this second that is fighting to get into detox. He looks like death. But he is still fighting. He isn’t a fool. He is his own hero. And he is someone’s son. He has value.
Sheilah

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really these current drug deaths …just what are you expecting people to do? there is no fear by the users

Independent of the tissue damage, xylazine is a potent alpha-2 agonist, and can drop your blood pressure through the floor.

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They just changed it to a controlled substance in PA.

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great. More paperwork and record keeping for the vet staff at your local clinic.

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This is exactly what my vet was saying when they were out doing routine stuff. They expect it to become a controlled substance that requires all that extra paperwork and record keeping and it will have to stay locked up in their truck, etc.

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I’m hoping dorm gel doesn’t become a controlled substance as well. It’s apparently in the same class of drugs as xylazine. Not sure if it can be abused in a similar fashion.

If you read the NYT article linked above, it discusses a bill moving through congress that would exempt veterinary use from the usual paperwork for scheduled drugs. It’s an actual bipartisan approach, amazing as that seems.

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AFAIK, the only use for xylazine is veterinary, and the DEA is perfectly happy to enforce the regulations on schedule drugs used in a veterinary setting, so not sure what that would look like.

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Wow… that looks like a horrible idea for human use.

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The article explains it.

All of a sudden, this is the topic of the day…

It’s usually not users mixing it, but the dealers. Many times the users don’t even really know what’s in the drug they bought.

Addiction is a scary thing. It will make you take risks no one normally would.

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NYT articles wants me to subscribe so…

People seem to like to link to NYT articles on this forum, after so many clicks they want people to subscribe.

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What benefit is there to the dealers in mixing this into fentanyl? I don’t understand how killing their clients is a good business decision.

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No, it does not.
There are specific DOJ/DEA regulations on record-keeping, storage, prescribing, and dispensing of controlled substances.
Necessary perhaps, but a PIA.
Adding xylazine to the list will necessitate following those rules.
None of that is discussed in the referenced article.

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Fentanyl has a relatively short duration of effect.
Xylazine slows cardiac output, respiratory rate, etc., and prolongs the “high”, apparently.

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That explanation makes sense, thank you!