Here’s part of what the 2004 Nursing Drug Handbook says about Prolixin, which is listed as an ANTI-PSYCHOTIC CNS drug, indicated for psychotic disorders:
[I]ACTION: Unknown. A piperazine phenothiazine that probably blocks postsynaptic dopamine in the brain.
ADVERSE REACTIONS: CNS: extrapyramidal reactions, tardive diskinesia, sedation, pseudoparkinsonism, EEG changes, drowsiness, seizures, dizziness, neuroleptic malignant syndrome. CV: orthostatic hypotension, tachycardia, ECG changes. EENT: ocular changes, blurred vision, nasal congestion…
Hematologic: leukopenia, agranulocytosis, eosinophilia, hemolytic anemia, aplastic anemia, thrombocytopenia. Hepatic: cholestatic jaundice.
NURSING CONSIDERATIONS: Monitor patient for tardive dyskinesia, which may occur after prolonged use. It may not appear until months or years later and may disappear spontaneously or persist for life, despite ending drug.
ALERT: Watch for evidence of neuroleptic malignant syndrome (extrapyramidal effects, hyperthermia, autonomic disturbance), which is rare but commonly fatal. It may not be related to length of drug use or type of neuroleptic…
After abrupt withdrawl of long-term therapy, gastritis, nausea, vomiting, dizziness, tremor, feeling of warmth or cold, diaphoresis (sweating), tachycardia, headache, or insomnia may occur.
PATIENT TEACHING: Warn patient to avoid activities that require alertness and good coordination until effects of drug are known. Drowsiness and dizziness usually subside after first few weeks.[/I]
Granted, this is for people and not horses…but, holy crap y’all, I wouldn’t want ANYONE giving this to my horse!
It is NOT indicated as a sedative, although it has that effect. It is an anti-psychotic drug used to treat people with psychosic disorders.
No wonder so many people are being suspended for using this. 
Okay, so having said I would never want this used on my horse, I then remembered that the Permax I used to treat my mare’s Cushing’s Syndrome is actually a human anti-Parkinsonian drug, most certainly a CNS drug with its own long list of scary human side effects. However, my mare was going to founder and probably DIE if I didn’t give her this drug, so there wasn’t much choice. It doesn’t seem to me that an ordinary, HEALTHY HORSE’S performance at a show is such a live-or-die scenario. 
“It’s not getting what you want, it’s wanting what you’ve got.” -Sheryl Crow
[This message was edited by sbt78lw on Nov. 07, 2003 at 10:51 PM.]